A case of fetal anticonvulsant syndrome with severe bilateral upper limb defect

Women with epilepsy have a higher risk of having a dysmorphic child. We report on a child exposed prenatally to valproate and carbamazepine presenting with severe bilateral upper limb defect and phenotypic features of fetal valproate syndrome. Anticonvulsant drugs can cause severe birth defects, esp...

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Bibliographic Details
Published in:The journal of maternal-fetal & neonatal medicine 2006-02, Vol.19 (2), p.115-117
Main Authors: Atahan Guven, Meli h, Batukan, Cem, Ceylaner, Serdar, Ceylaner, Gülay, Uzel, Murat
Format: Article
Language:English
Subjects:
Abnormalities, Drug-Induced - etiology
Adult
Anticonvulsants - adverse effects
Carbamazepine - adverse effects
Epilepsy - drug therapy
Female
Fetal Diseases - chemically induced
Humans
Infant, Newborn
Limb Deformities, Congenital - chemically induced
Pregnancy
Valproic Acid - adverse effects
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Summary:Women with epilepsy have a higher risk of having a dysmorphic child. We report on a child exposed prenatally to valproate and carbamazepine presenting with severe bilateral upper limb defect and phenotypic features of fetal valproate syndrome. Anticonvulsant drugs can cause severe birth defects, especially when used in combination.
ISSN:1476-7058
1476-4954
DOI:10.1080/14767050500420665