The coxsackievirus and adenovirus receptor is a transmembraine component of the tight junction

The coxsackievirus and adenovirus receptor (CAR) mediates viral attachement and infection ,but its physiologic functions ahve not been described. In nonpolarized cells, CAR localized to homotypic intercellular contacts, mediated homotypic cell aggregation, and recruited the tight junction protein Zo...

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Bibliographic Details
Published in:Proceedings of the National Academy of Sciences - PNAS 2001-12, Vol.98 (26), p.15191
Main Authors: Cohen, Christopher J, Shieh, Joseph T C, Pickles, Raymond J, Okegawa, Takatsugu
Format: Article
Language:English
Subjects:
Cells
Viruses
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Summary:The coxsackievirus and adenovirus receptor (CAR) mediates viral attachement and infection ,but its physiologic functions ahve not been described. In nonpolarized cells, CAR localized to homotypic intercellular contacts, mediated homotypic cell aggregation, and recruited the tight junction protein Zo-1 to sites of cell-cell contact.
ISSN:0027-8424
1091-6490