BIOMECHANICS AND DRUG ELUTION IN ARTERIAL RESPONSE TO PERIPHERAL STENTS: AN OCT COMPARATIVE STUDY OF 3 CONTEMPORARY STENTS IN BALLOON-PREDILATED FEMORAL ARTERIES OF FAMILIAL HYPERCHOLESTEROLEMIC SWINE

Methods Twenty-four iliofemoral arteries of 11 FHS were balloon-predilated on day 0 followed by implantation of self-expanding stents: a novel fluoropolymer-coated nitinol paclitaxel-eluting stent (Eluvia, Boston Scientific, n=7), a helical interwoven nitinol wire stent (Supera, Abbott Vascular, n=7...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2018-03, Vol.71 (11), p.A1232-A1232
Main Authors: Cheng, Yanping, McGregor, Jennifer, Conditt, Gerard, Montero-Baker, Miguel, Kaluza, Greg, Granada, Juan
Format: Article
Language:English
Subjects:
Arteries
Balloon treatment
Biomechanics
Cardiology
Comparative studies
Elution
Femoral artery
Femur
Implants
Livestock
Medical imaging
Stents
Surgical implants
Swine
Veins & arteries
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Summary:Methods Twenty-four iliofemoral arteries of 11 FHS were balloon-predilated on day 0 followed by implantation of self-expanding stents: a novel fluoropolymer-coated nitinol paclitaxel-eluting stent (Eluvia, Boston Scientific, n=7), a helical interwoven nitinol wire stent (Supera, Abbott Vascular, n=7) and a conventional nitinol stent (EverFlex, Medtronic, n=8). Conclusion When assessed by OCT after 90 days from implantation, the Eluvia nitinol self-expanding paclitaxel-eluting stent had highest late stent expansion compared to the Supera stent, and significantly contained 90 day neointimal proliferation in comparison to the conventional EverFlex nitinol stent in predilated femoral arteries of the FHS.
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(18)31773-X