PLEIOTROPIC EFFECTS OF THE EXOSOMES FROM IPSC-DERIVATIVES IN RESTORING INJURED MYOCARDIUM

[...]CD1 mice (n=5/group) underwent left anterior descending artery ligation and were injected with the exosomes in the peri-infarct region. In vitro study demonstrated that the lower dose of the exosomes (104/ml) showed cardioprotective effect on the hypoxia-injury model of iCMs as well as the high...

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Published in:Journal of the American College of Cardiology 2018-03, Vol.71 (11), p.A80-A80
Main Authors: Vaskova, Evgeniya, Tada, Yuko, von Bornstaedt, Daniel, Woo, Y., Yang, Phillip
Format: Article
Language:English
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Summary:[...]CD1 mice (n=5/group) underwent left anterior descending artery ligation and were injected with the exosomes in the peri-infarct region. In vitro study demonstrated that the lower dose of the exosomes (104/ml) showed cardioprotective effect on the hypoxia-injury model of iCMs as well as the highest angiogenic potential.
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(18)30621-1