Developing Clinical Guidelines/Reply

The best exemplar is the comparison of meta-analysis with subsequent large randomized controlled trial by LeLorier and colleagues (2), where simple data aggregation was little better than flipping a coin in predicting true clinical outcome.A comparative analysis of pulmonary and critical care medici...

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Published in:American journal of respiratory and critical care medicine 2018-03, Vol.197 (6), p.837-838
Main Authors: Morice, Alyn H, Hart, Simon, Millqvist, Eva, Schoenberg, Noah C, Wilson, Kevin C
Format: Article
Language:English
Subjects:
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Critical care
Editorials
Medicine
Systematic review
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Summary:The best exemplar is the comparison of meta-analysis with subsequent large randomized controlled trial by LeLorier and colleagues (2), where simple data aggregation was little better than flipping a coin in predicting true clinical outcome.A comparative analysis of pulmonary and critical care medicine guideline development methodologies.Noah C. Schoenberg, M.D. Kevin C. Wilson, M.D. Boston University School of Medicine Boston, Massachusetts Originally Published in Press as DOI: 10.1164/rccm.201710-2039LE on October 31, 2017 References 1.A comparative analysis of pulmonary and critical care medicine guideline development methodologies.
ISSN:1073-449X
1535-4970
DOI:10.1164/rccm.201708-1754LE