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Prognostic Significance of the Number of Removed Lymph Nodes in Pathologic Node-Negative Non-small Cell Lung Cancer

Major lung resection combined with mediastinal lymph node dissection is the standard operation for early-stage non-small cell lung cancer (NSCLC), and lymph node staging is the main predictor of long-term survival. This study aims to identify the prognostic significance of the number of removed lymp...

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Bibliographic Details
Published in:Indian journal of surgery 2019-04, Vol.81 (2), p.137-143
Main Authors: Wu, Xian-Ning, Xie, Ming-Ran, Xu, Shi-Bin, Wang, Jun, Jiang, Xian-Liang, Xu, Mei-Qing
Format: Article
Language:English
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Summary:Major lung resection combined with mediastinal lymph node dissection is the standard operation for early-stage non-small cell lung cancer (NSCLC), and lymph node staging is the main predictor of long-term survival. This study aims to identify the prognostic significance of the number of removed lymph nodes in patients with pathologic node-negative (pN0) non-small cell lung cancer (NSCLC). Five hundred thirty-six stage pN0 NSCLC patients, received curative resection between January 2004 and July 2011, were enrolled in this retrospective study. The prognostic factors including the number of removed lymph nodes and clinicopathological characteristics were analyzed. Increasing number of removed lymph nodes was associated with better overall survival (OS) ( p  = 0.009) of stage pN0 NSCLC patients. The number ( p  
ISSN:0972-2068
0973-9793
DOI:10.1007/s12262-018-1746-z