Development of biosensor for detection of serum creatinine

Serum creatinine is an established biochemical marker for monitoring of renal function. Analytical methods to detect creatinine concentration have been investigated as early as 1886. However, majority of these methods involve sophisticated instrumentation which limits its accessibility to economical...

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Bibliographic Details
Published in:CSI TRANSACTIONS ON ICT 2018, Vol.6 (1), p.5-10
Main Authors: Dasgupta, Pallavi, Kumar, Vinay, Krishnaswamy, P. R., Bhat, Navakanta
Format: Article
Language:English
Subjects:
Accessibility
Biosensors
Cost analysis
Creatinine
Instruments
Low cost
Renal function
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Summary:Serum creatinine is an established biochemical marker for monitoring of renal function. Analytical methods to detect creatinine concentration have been investigated as early as 1886. However, majority of these methods involve sophisticated instrumentation which limits its accessibility to economically challenged patients. In this regard, point of care biosensors provide a low-cost solution coupled with simple instrumentation. There has been growing interest in development of point-of-care technology (POCT) devices for creatinine estimation. However, majority of these POCT devices are enzymatic assays, which add to the complexity and the cost. In this work, we aim to develop non-enzymatic electrochemical creatinine biosensor which simplifies the process of routine clinical analysis, and thereby making it accessible due to its low-cost.
ISSN:2277-9078
2277-9086
DOI:10.1007/s40012-018-0187-y