Analysis of clinical features and visual outcomes of pars planitis

• Published in: International ophthalmology 2018-04, Vol.38 (2), p.727-736
• Main Authors: Berker, Nilufer, Sen, Emine, Elgin, Ufuk, Atilgan, Cemile Ucgul, Dursun, Erdem, Yilmazbas, Pelin
• Format: Article
• Language: English
• Subjects: Adolescents; Anterior chamber; Cataracts; Children; Complications; Corticoids; Corticosteroids; Demographics; Edema; Eye; Eye (anatomy); Glaucoma; Haze; Hemorrhage; Medical records; Medicine; Medicine & Public Health; Ophthalmology; Original Paper; Patients; Retina; Sheathing; Statistical analysis; Uveitis
• ISSN: 0165-5701; 1573-2630
• DOI: 10.1007/s10792-017-0526-2

Purpose To evaluate the demographic characteristics, clinical features, treatment and outcomes of patients with pars planitis in a tertiary referral center in Turkey. Methods Medical records of patients with pars planitis were retrospectively reviewed. The data including demographic and ocular features and treatment outcomes were recorded. The distribution of clinical findings and complications were evaluated according to age and gender groups. The changes in final BCVA compared to the initial BCVA were noted. Statistical analysis was performed using SPSS software (Version 18.0, SPSS Inc., Chicago, USA). Results Twenty-seven patients (54 eyes) were included in this study. 16 patients were male (59.3%), and 11 were female (40.7%). Mean age at diagnosis was 12.84 ± 8.26 (range 4–36) years. Mean follow-up period was 61.3 ± 52.15 (range 9–172) months. Mean BCVA was 0.58 ± 0.36 (range 0.03–1.00) (0.40 ± 0.45 logMAR) at presentation, and 0.81 ± 0.28 (range 0.10–1.00) (0.14 ± 0.27 logMAR) at final visit ( P  = 0.001). Vitreous inflammation (100%), vitreous haze (92.6%), snowballs (74.1%), snowbanks (66.7%), anterior chamber cells (66.7%) and peripheral retinal vascular sheathing (48.1%) were the most common presentations. Ocular complications included vitreous condensation (51.9%), cystoid macular edema (22.2%), cataract (18.5%), inferior peripheral retinal detachment (11.1%), glaucoma (5.6%) and vitreous hemorrhage (3.7%). Treatments included topical, periocular, intravitreal and systemic corticosteroids, immunosuppressives, peripheral laser photocoagulation and pars plana vitrectomy when needed. Conclusions Pars planitis is an idiopathic chronic intermediate uveitis mostly affecting children and adolescents. In spite of its chronic nature with high potential of causing ocular complications, adequate treatment and close follow-up lead to favorable visual outcomes.