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The capacity and effectiveness of diosmectite and charcoal in trapping the compounds causing the most frequent intoxications in acute medicine: A comparative study

Highlights • Promethazine and imipramine are the most effectively adsorbed to diosmectite. • The acidic drugs (acetylsalicylic acid) are poorly adsorbed onto diosmectite. • Diosmectite and charcoal mostly behave independently or in a bit antagonistic way.

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Bibliographic Details
Published in:Environmental toxicology and pharmacology 2017-06, Vol.52, p.214-220
Main Authors: Mináriková, Michaela, Fojtikova, Veronika, Vyskočilová, Eliška, Sedláček, Jan, Šikut, Milan, Borek-Dohalska, Lucie, Stiborová, Marie, Martinkova, Marketa
Format: Article
Language:English
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Summary:Highlights • Promethazine and imipramine are the most effectively adsorbed to diosmectite. • The acidic drugs (acetylsalicylic acid) are poorly adsorbed onto diosmectite. • Diosmectite and charcoal mostly behave independently or in a bit antagonistic way.
ISSN:1382-6689
1872-7077
DOI:10.1016/j.etap.2017.04.011