Carbon cloth-supported cobalt phosphide as an active matrix for constructing enzyme-based biosensor

• Published in: Journal of solid state electrochemistry 2018-06, Vol.22 (6), p.1689-1696
• Main Authors: Dong, Sheying, Yang, Qiangxu, Fu, Yile, Zhang, Dandan, Huang, Tinglin
• Format: Article
• Language: English
• Subjects: Aluminum; Analytical Chemistry; Biosensors; Carbon; Catalysis; Catalytic activity; Characterization and Evaluation of Materials; Chemistry; Chemistry and Materials Science; Cloth; Cobalt; Condensed Matter Physics; Electrochemistry; Energy Storage; Enzymes; Hemoglobin; Hydrogen peroxide; Matrices (mathematics); Nanowires; Original Paper; Phosphides; Physical Chemistry; Product development
• ISSN: 1432-8488; 1433-0768
• DOI: 10.1007/s10008-017-3864-0

A self-supported nanoporous cobalt phosphide (CoP) nanowire arrays on the carbon cloth (CC) as an active matrix was fabricated and utilized as an interface for the construction of hemoglobin (Hb)-based biosensors. This matrix was wrapped in a thin aluminum sheet by handmade. Moreover, the electrochemistry and electrocatalytic properties of Hb were investigated on such a matrix. The results revealed that the self-supported nanoporous CoP nanowire arrays on CC significantly enhanced the electrochemical responses of Hb. In the meantime, the immobilized Hb remained its good bioactivity and high catalytic activity to hydrogen peroxide (H 2 O 2 ). This matrix is thus a suitable platform to develop highly sensitive enzyme-based biosensor, which has the linear range of H 2 O 2 concentration from 2 to 2670 μM with a detection limit of 0.7 μM (S/ N  = 3). Consequently, it is desirable to explore the possibility of developing a kind of simpler and cheaper matrix electrode.