The extracellular proteases produced by Vibrio parahaemolyticus

Vibrio parahaemolyticus , a Gram-negative bacterium, inhabits marine and estuarine environments and it is a major pathogen responsible globally for most cases of seafood-associated gastroenteritis in humans and acute hepatopancreatic necrosis syndrome in shrimps. There has been a dramatic worldwide...

Full description

Saved in:
Bibliographic Details
Published in:World journal of microbiology & biotechnology 2018-05, Vol.34 (5), p.68-7, Article 68
Main Authors: Osei-Adjei, George, Huang, Xinxiang, Zhang, Yiquan
Format: Article
Language:English
Subjects:
Animals
Applied Microbiology
Bacterial Proteins - biosynthesis
Bacterial Proteins - genetics
Bacterial Proteins - secretion
Biochemistry
Biomedical and Life Sciences
Biotechnology
Environmental Engineering/Biotechnology
Estuaries
Estuarine environments
Gastroenteritis
Humans
Life Sciences
Metalloproteases - biosynthesis
Metalloproteases - genetics
Metalloproteases - secretion
Microbiology
Pathogenicity
Pathogens
Peptide Hydrolases - biosynthesis
Peptide Hydrolases - classification
Peptide Hydrolases - genetics
Peptide Hydrolases - secretion
Proteases
Proteins
Review
Seafood
Seafood - microbiology
Seawater
Serine
Serine Proteases - biosynthesis
Serine Proteases - genetics
Serine Proteases - secretion
Shrimps
Vibrio Infections - microbiology
Vibrio parahaemolyticus
Vibrio parahaemolyticus - enzymology
Vibrio parahaemolyticus - genetics
Vibrio parahaemolyticus - pathogenicity
Virulence
Virulence factors
Virulence Factors - genetics
Virulence Factors - metabolism
Waterborne diseases
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Vibrio parahaemolyticus , a Gram-negative bacterium, inhabits marine and estuarine environments and it is a major pathogen responsible globally for most cases of seafood-associated gastroenteritis in humans and acute hepatopancreatic necrosis syndrome in shrimps. There has been a dramatic worldwide increase in V. parahaemolyticus infections over the last two decades. The pathogenicity of V. parahaemolyticus has been linked to the expression of different kinds of virulence factors including extracellular proteases, such as metalloproteases and serine proteases. V. parahaemolyticus expresses the metalloproteases; PrtV, VppC, VPM and the serine proteases; VPP1/Protease A, VpSP37, PrtA. Extracellular proteases have been identified as potential virulence factors which directly digest many kinds of host proteins or indirectly are involved in the processing of other toxic protein factors. This review summarizes findings on the metalloproteases and serine proteases produced by V. parahaemolyticus and their roles in infections. Identifying the role of V. parahaemolyticus virulence-associated extracellular proteases deepens our understanding of diseases caused by this bacterium.
ISSN:0959-3993
1573-0972
DOI:10.1007/s11274-018-2453-4