Dynamics in 18-fluoromisonidazole PET/CT and perfusion-weighted 3-Tesla MRI parameters as biomarkers for predicting treatment outcome in HNSCC

An abstract of the study conducted by Bunea et al detecting the dynamics of hypoxia during chemoradiation (RCTx) is with FMISO PET/CT and correlated to perfusion MRI parameters is presented. Bunea et al concluded that changes in SUVmax are crucial in week 2 and in the limited patient cohort and the...

Full description

Saved in:
Bibliographic Details
Published in:European journal of cancer (1990) 2016-12, Vol.69, p.S60-S60
Main Authors: Bunea, H, Bunea, A, Wiedenmann, N, Stoykow, C, Mix, M, Majerus, L, Ludwig, U, Rischke, H.C, Langer, M, Meyer, P.T, Bock, M, Grosu, A.L
Format: Article
Language:English
Subjects:
Biomarkers
Chemoradiotherapy
Chemotherapy
Head & neck cancer
Hematology, Oncology and Palliative Medicine
Hypoxia
Magnetic resonance imaging
Medical imaging
NMR
Nuclear magnetic resonance
Parameters
Perfusion
Positron emission
Radiation therapy
Squamous cell carcinoma
Tomography
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:An abstract of the study conducted by Bunea et al detecting the dynamics of hypoxia during chemoradiation (RCTx) is with FMISO PET/CT and correlated to perfusion MRI parameters is presented. Bunea et al concluded that changes in SUVmax are crucial in week 2 and in the limited patient cohort and the short FU, they found that a decrease in Ktrans might indicate a poorer outcome and stated that the finding markers in bioimaging may allow individualization of treatment by dose painting and adaptive radiotherapy.
ISSN:0959-8049
1879-0852
DOI:10.1016/S0959-8049(16)32768-X