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Texture analysis as a predictor of radiation-induced xerostomia in head and neck patients undergoing IMRT

Purpose Image texture analysis (TA) is a heterogeneity quantifying approach that cannot be appreciated by the naked eye, and early evidence suggests that TA has great potential in the field of oncology. The aim of this study is to evaluate parotid gland texture analysis (TA) combined with formal dos...

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Bibliographic Details
Published in:Radiologia medica 2018-06, Vol.123 (6), p.415-423
Main Authors: Nardone, Valerio, Tini, Paolo, Nioche, Christophe, Mazzei, Maria Antonietta, Carfagno, Tommaso, Battaglia, Giuseppe, Pastina, Pierpaolo, Grassi, Roberta, Sebaste, Lucio, Pirtoli, Luigi
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Language:English
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Summary:Purpose Image texture analysis (TA) is a heterogeneity quantifying approach that cannot be appreciated by the naked eye, and early evidence suggests that TA has great potential in the field of oncology. The aim of this study is to evaluate parotid gland texture analysis (TA) combined with formal dosimetry as a factor for predicting severe late xerostomia in patients undergoing radiation therapy for head and neck cancers. Methods We performed a retrospective analysis of patients treated at our Radiation Oncology Unit between January 2010 and December 2015, and selected the patients whose normal dose constraints for the parotid gland (mean doseĀ 
ISSN:0033-8362
1826-6983
DOI:10.1007/s11547-017-0850-7