Effect of Ixora coccinea flowers on dead space wound healing in rats

The alcoholic extract of the flowers of Ixora coccinea was studied for its effect on wound healing, using a dead space wound model in rats. Significant increases in granuloma tissue weight, tensile strength, hydroxyproline and glycosaminoglycan content were observed. The prohealing actions seem to b...

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Bibliographic Details
Published in:Fitoterapia 1999-06, Vol.70 (3), p.233-236
Main Authors: Nayak, B.S., Udupa, A.L., Udupa, S.L.
Format: Article
Language:English
Subjects:
Biological and medical sciences
General pharmacology
Ixora coccinea
Medical sciences
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Wound healing activity
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Summary:The alcoholic extract of the flowers of Ixora coccinea was studied for its effect on wound healing, using a dead space wound model in rats. Significant increases in granuloma tissue weight, tensile strength, hydroxyproline and glycosaminoglycan content were observed. The prohealing actions seem to be due to increased collagen deposition as well as better alignment and maturation. The drug induced a hypertropic effect on the thymus gland but had no effect on the adrenals.
ISSN:0367-326X
1873-6971
DOI:10.1016/S0367-326X(99)00025-8