Identifying peptide sequences that can control the assembly of gold nanostructures

This study is about how peptide sequences can control the assembly and growth of gold nanomaterials. Two cysteine-containing sequences, YYCYY and glutathione (GSH), have been newly identified as assembly motifs to control the resulting two-dimensional (2D) morphology. Cysteine interacts with gold io...

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Bibliographic Details
Published in:Molecular systems design & engineering 2018-06, Vol.3 (3), p.581-590
Main Authors: Lee, Hye-Eun, Lee, Jaehun, Ju, Misong, Ahn, Hyo-Yong, Lee, Yoon Young, Jang, Hyung-Seok, Nam, Ki Tae
Format: Article
Language:English
Subjects:
Assembly
Cysteine
Glutathione
Gold
Morphology
Nanomaterials
Peptides
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Summary:This study is about how peptide sequences can control the assembly and growth of gold nanomaterials. Two cysteine-containing sequences, YYCYY and glutathione (GSH), have been newly identified as assembly motifs to control the resulting two-dimensional (2D) morphology. Cysteine interacts with gold ions and the gold surface to initiate nucleation and control growth. YYCYY forms a flat, 2D, gold-decorated film and GSH results in twisted, petal-like structures. By conducting a comparative study of these two sequences, the important role of peptide folding in the gold atom assembly process is investigated.
ISSN:2058-9689
2058-9689
DOI:10.1039/C7ME00091J