Wetting ability of human blood in the presence of gold nanoparticles

Gold nanoparticles are more and more used in bio-medical field for their advantages to be employed as contrast medium for diagnostic images and as targets of disease cells in which thermal-therapy or radiotherapy must be applied. In this contest, a suitable concentration of nanoparticles was added t...

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Bibliographic Details
Published in:Gold bulletin (World Gold Council) 2018-09, Vol.51 (3), p.111-121
Main Authors: Torrisi, L., Scolaro, C., Restuccia, N.
Format: Article
Language:English
Subjects:
Biocompatibility
Blood
Chemistry and Materials Science
Diagnostic systems
Gold
Human performance
Image contrast
Materials Science
Metallic Materials
Nanoparticles
Organs
Original Paper
Particle size distribution
Physical properties
Radiation therapy
Solid surfaces
Target recognition
Viscosity
Wetting
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Summary:Gold nanoparticles are more and more used in bio-medical field for their advantages to be employed as contrast medium for diagnostic images and as targets of disease cells in which thermal-therapy or radiotherapy must be applied. In this contest, a suitable concentration of nanoparticles was added to human blood to study in vitro some physical properties of the treated liquid which is prepared to transport the nanoparticles to the different organs where they can be accumulated by metabolic effects. Measurements indicated that the insertion of gold nanoparticles in the human blood improves the blood wetting ability. In particular, the wetting ability of the blood containing or not gold nanoparticles, with respect to different biocompatible solid surfaces, was investigated. Also, the density, tension surface, and viscosity of the solution at room temperature were measured. Results demonstrated that the introduction of gold nanoparticles in the blood, with size distribution centered at about 50 nm, generally improves the wetting ability and changes other properties of the solution, due to the different distributions of the cohesion and adhesion forces.
ISSN:2364-821X
2190-7579
DOI:10.1007/s13404-018-0236-1