Wild chamomile ( Matricaria recutita L.) mouthwashes in methotrexate-induced oral mucositis

Oral mucositis is a known complication of methotrexate (MTX) therapy, but a single efficacious intervention or agent for prophylaxis or management of this side effect has not yet been identified. We report a case of MTX-induced oral mucositis in a patient with rheumatoid arthritis, who was successfu...

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Bibliographic Details
Published in:Phytomedicine (Stuttgart) 2005, Vol.12 (1), p.25-27
Main Authors: Mazokopakis, E.E., Vrentzos, G.E., Papadakis, J.A., Babalis, D.E., Ganotakis, E.S.
Format: Article
Language:English
Subjects:
adverse effects
Aged
anti-inflammatory activity
Anti-Inflammatory Agents, Non-Steroidal - administration & dosage
Anti-Inflammatory Agents, Non-Steroidal - therapeutic use
Antifungal agents
Antimitotic agents
Antineoplastic agents
Aplastic anaemia
aqueous solutions
Arthritis, Rheumatoid - drug therapy
Cell research
Complications and side effects
Corticosteroids
Dentifrices
digestive tract mucosa
Dosage and administration
Female
Flowers
Humans
Immunosuppressive Agents - administration & dosage
Immunosuppressive Agents - adverse effects
inflammation
Matricaria
Matricaria recutita
Matricaria recutita L
medicinal plants
Medicine, Botanic
Medicine, Herbal
Methotrexate
Methotrexate - administration & dosage
Methotrexate - adverse effects
mouth
mouthwashes
Mouthwashes - administration & dosage
Mouthwashes - therapeutic use
Oral hygiene products
Oral mucositis
Phytotherapy
plant extracts
Plant Extracts - administration & dosage
Plant Extracts - therapeutic use
Stomatitis - chemically induced
Stomatitis - drug therapy
Toiletries industry
topical application
Wild chamomile
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Description
Summary:Oral mucositis is a known complication of methotrexate (MTX) therapy, but a single efficacious intervention or agent for prophylaxis or management of this side effect has not yet been identified. We report a case of MTX-induced oral mucositis in a patient with rheumatoid arthritis, who was successfully treated with Wild chamomile mouthwashes.
ISSN:0944-7113
1618-095X
DOI:10.1016/j.phymed.2003.11.003