Influence of grape variety and their phenolic composition on vasorelaxing activity of young red wines

Red wine has been reported to exert beneficial effects in preventing cardiovascular diseases probably due to their polyphenols constituents. The vasorelaxant capacity and phenolic composition of four monovarietal young red wines Merlot, Tempranillo, Garnacha and Cabernet-Sauvignon obtained from grap...

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Bibliographic Details
Published in:European food research & technology 2008-10, Vol.227 (6), p.1641-1650
Main Authors: Ortega, Teresa, De La Hera, Elena, Carretero, M. Emilia, Gómez-Serranillos, Pilar, Naval, M. Victoria, Villar, Angel M, Prodanov, Marin, Vacas, Visitación, Arroyo, Teresa, Hernández, Teresa, Estrella, Isabel
Format: Article
Language:English
Subjects:
Agriculture
Analytical Chemistry
Biological and medical sciences
Biotechnology
Cabernet-Sauvignon
Cardiovascular diseases
Chemistry
Chemistry and Materials Science
Endothelium
Fermentation
Fermented food industries
Food
Food industries
Food Science
Forestry
Fruit and vegetable industries
Fundamental and applied biological sciences. Psychology
Garnacha
Liquid chromatography
Merlot
Mortality
Nitric oxide
Original Paper
Phenolic composition
Phenols
Polyphenols
Smooth muscle
Studies
Tempranillo
vasodilation
Vasoprotective
Wines
Wines and vinegars
Young monovarietal wine
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Summary:Red wine has been reported to exert beneficial effects in preventing cardiovascular diseases probably due to their polyphenols constituents. The vasorelaxant capacity and phenolic composition of four monovarietal young red wines Merlot, Tempranillo, Garnacha and Cabernet-Sauvignon obtained from grapes from 2004 vintage, cultivated under the same climatic and agricultural conditions, wine-making technology and storage conditions, were determined using vascular reactivity assay in rat aortic and high-performance liquid chromatography, respectively. Primary cultures of vascular smooth muscle cells from Wistar rats were also used to evaluate their survival prevention activity as well. Every studied wine present vasorelaxation effect, but the higher value corresponds to the analyzed Merlot wine, especially rich in phenolic compounds, mainly catechins and oligomeric proanthocyanidins and anthocyanin glycosides. This study further demonstrated previous investigations about the phenolic composition of wines relation with their vasorelaxation activity.
ISSN:1438-2377
1438-2385
DOI:10.1007/s00217-008-0888-9