Histopathological lesions and toxicity in common carp (Cyprinus carpio L. 1758) induced by copper nanoparticles

• Published in: Microscopy research and technique 2018-07, Vol.81 (7), p.724-729
• Main Authors: Forouhar Vajargah, Mohammad, Mohamadi Yalsuyi, Ahmad, Hedayati, Aliakbar, Faggio, Caterina, Diaspro, Alberto
• Format: Article
• Language: English
• Subjects: Agrochemicals; Animals; Aquatic organisms; Carp; Carps; Copper; Copper - toxicity; copper oxide; Copper oxides; Cyprinus carpio; Darkening; Erythrocytes; Fish; gill damages; Gills - drug effects; Gills - pathology; heavy metal; Hyperplasia; Hypertrophy; Infiltration; Kidney - drug effects; Kidney - pathology; Lesions; Liver - drug effects; Liver - pathology; Metal Nanoparticles - toxicity; Mortality; Nanoparticles; Oxides; Pesticides; Regression analysis; Skin; Skin - drug effects; Skin - pathology; Statistical analysis; Statistical methods; Toxicity; Water treatment
• ISSN: 1059-910X; 1097-0029
• DOI: 10.1002/jemt.23028

Different types of metal oxide nanoparticles (NPs) have been suggested for various applications such as water treatment and construction of agricultural pesticides; however, there are concerns about the potential toxicity of these compounds for the nontarget organism especially aquatic organisms. The aims of this study were assessing toxicity and histopathological effects of copper oxide NPs (NPs‐CuO) on common carp (Cyprinus carpio) as a model organism. For this purpose 150 common carp with an average weight 7 ± 1 g were exposed to 0, 10, 20, 30, 40, 60, 80, 100, 150, and 200 mg/l of CuO‐NPs (10 treatment with three replicates) for 96 hrs. After 24, 48, 72, and 96 hrs exposures, mortality rates recorded and gill samples were collected. Statistical analysis showed significant differences in carp survival between control and treatment groups (p