Hypocholesterolemic effect of camel milk on rats fed a high-cholesterol diet

The effects of fermented skim milk versus unfermented skim milk of camel on the levels of cholesterol in blood were investigated in rats. Levels of serum cholesterol and LDL-C/ HDL-C ratio were decreased significantly in Wistar rats that fed with a cholesterol-enriched diet and administered fermente...

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Published in:Emirates journal of food and agriculture 2018-04, Vol.30 (4), p.288-294
Main Authors: Yahya, Mohammed A., Alhaj, Omar A., AL-Khalifah, Abdullrahman S., Almnaizel, Ahmad T.
Format: Article
Language:English
Subjects:
Amino acids
Apoptosis
Atherosclerosis
Cardiovascular disease
Cholesterol
Degeneration
Diet
Enzymes
Experiments
Fibrosis
Food
High cholesterol diet
High density lipoprotein
Hypercholesterolemia
Hyperlipidemia
Laboratory animals
Lactobacillus helveticus
Lactobacillus plantarum
Lactose
Lipids
Liver
Low density lipoprotein
Microorganisms
Milk
Nutrition research
Peptides
Pharmacy
Probiotics
Proteins
Rats
Reagents
Risk reduction
Rodents
Skim milk
Steatosis
Streptococcus thermophilus
Triglycerides
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container_issue 4
container_start_page 288
container_title Emirates journal of food and agriculture
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creator Yahya, Mohammed A.
Alhaj, Omar A.
AL-Khalifah, Abdullrahman S.
Almnaizel, Ahmad T.
description The effects of fermented skim milk versus unfermented skim milk of camel on the levels of cholesterol in blood were investigated in rats. Levels of serum cholesterol and LDL-C/ HDL-C ratio were decreased significantly in Wistar rats that fed with a cholesterol-enriched diet and administered fermented skim camel milk compared with rats administered unfermented milk (P˂0.05). Furthermore, histopathological evaluation showed that liver tissue degeneration, apoptosis/necrosis, inflammation, and fatty changes (steatosis and fibrosis) decreased significantly at (P˂0.05) in the rats that fed with fermented skim camel milk compared to the rats which fed unfermented skim camel milk. Based on these results it can suggest that fermented skim camel milk might reduce the risk of hypercholesterolemia development in rats. The hypocholesterolemic and hepatoprotective effects of fermented skim camel milk were evident.
doi_str_mv 10.9755/ejfa.2018.v30.i4.1664
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identifier ISSN: 2079-052X
ispartof Emirates journal of food and agriculture, 2018-04, Vol.30 (4), p.288-294
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2079-0538
language eng
recordid cdi_proquest_journals_2062947306
source Publicly Available Content (ProQuest)
subjects Amino acids
Apoptosis
Atherosclerosis
Cardiovascular disease
Cholesterol
Degeneration
Diet
Enzymes
Experiments
Fibrosis
Food
High cholesterol diet
High density lipoprotein
Hypercholesterolemia
Hyperlipidemia
Laboratory animals
Lactobacillus helveticus
Lactobacillus plantarum
Lactose
Lipids
Liver
Low density lipoprotein
Microorganisms
Milk
Nutrition research
Peptides
Pharmacy
Probiotics
Proteins
Rats
Reagents
Risk reduction
Rodents
Skim milk
Steatosis
Streptococcus thermophilus
Triglycerides
title Hypocholesterolemic effect of camel milk on rats fed a high-cholesterol diet
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