Electrochemical biosensors for influenza virus a detection: The potential of adaptation of these devices to POC systems

• Published in: Sensors and actuators. B, Chemical Chemical, 2018-01, Vol.254, p.377-384
• Main Authors: Tepeli, Yudum, Ülkü, Anik
• Format: Article
• Language: English
• Subjects: Biosensors; Diagnostic systems; Electrochemical biosensors; Hemagglutinin; Influenza; Influenza virus A; Medical diagnosis; Neuraminidase; Point of care diagnosis; Viruses
• ISSN: 0925-4005; 1873-3077
• DOI: 10.1016/j.snb.2017.07.126

[Display omitted] The illustration of the influenza virüs A path in the host cells. •Information about the structure, species and pandemics of influenza A virus has been presented.•The invasion of host cells by this virus is explained.•Conventional detection methods have been discussed.•Existing electrochemical influenza A virus biosensors have been critically evaluated.•The prospects of electrochemical influenza A virus biosensors have been critically evaluated. Influenza virus A still causes serious pandemics every year which result in high mortality. Though there are promising developments involving newly emerged diagnostic tests for the detection of this virus, the “perfect” test has not been developed yet. In this review, we focus on the electrochemical biosensors for influenza virus A detection. Firstly, brief information about structure, species and pandemics of influenza virus A has been presented. After elucidating the invasion of host cells with this virus, conventional detection methods have been discussed. Then, definition of electrochemical biosensors was made and the existing electrochemical influenza virus A biosensors have been critically evaluated. Lastly, the prospects of electrochemical influenza virus A biosensor in POC technology have been discussed.