Simulations and Image Reconstruction for the High Resolution CaLIPSO PET Scanner for Brain and Preclinical Studies

The foreseen CaLIPSO Positron Emission Tomography (PET) scanner is expected to yield simultaneously a fine image resolution, about 1 mm\(^3\), and a high contrast. In this paper we present results of simulations for the full CaLIPSO PET scanner with a "cube" geometry. We quantify by simula...

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Bibliographic Details
Published in:arXiv.org 2018-01
Main Authors: Kochebina, Olga, Jan, Sébastien, Stute, Simon, Sharyy, Viatcheslav, Verrecchia, Patrice, Mancardi, Xavier, Yvon, Dominique
Format: Article
Language:English
Subjects:
Brain
Emission analysis
High resolution
Image contrast
Image reconstruction
Image resolution
Medical imaging
Positron emission
Scanners
Simulation
Spatial resolution
Tomography
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Summary:The foreseen CaLIPSO Positron Emission Tomography (PET) scanner is expected to yield simultaneously a fine image resolution, about 1 mm\(^3\), and a high contrast. In this paper we present results of simulations for the full CaLIPSO PET scanner with a "cube" geometry. We quantify by simulations the expected image resolution and Noise Equivalent Count Rates and compare them to the performance of the most efficient clinically used PET scanner, the High-Resolution Research Tomograph by Siemens. We bring up the issues of the image reconstruction for a scanner with high spatial resolution. We also present simulated brain images for [\(^{18}\)F]-FDG and [\(^{11}\)C]-PE2I tracer distributions. Results demonstrate the high potential of the CaLIPSO PET scanner for small animal and brain imaging where combination of high spatial resolution and efficiency is essential.
ISSN:2331-8422