Fabrication of nickel coated graphene oxide composite electrode for sensitive determination of Rutin

• Published in: Journal of electroanalytical chemistry (Lausanne, Switzerland) Switzerland), 2018-04, Vol.815, p.76-85
• Main Authors: Karabiberoğlu, Şükriye Ulubay, Dursun, Zekerya
• Format: Article
• Language: English
• Subjects: Analytical chemistry; Carbon; Coated electrodes; Electrocatalysis; Electrochemical analysis; Electrochemical impedance spectroscopy; Electrodes; Formulations; Glassy carbon; Graphene; Graphene oxide; Metal nanoparticle; Metal oxides; Morphology; Nickel compounds; Nickel oxide; Organic chemistry; Organic compounds; Resistance; Rutin; Scanning electron microscopy; Square waves; Transmission electron microscopy; Voltammetry; X ray photoelectron spectroscopy
• ISSN: 1572-6657; 1873-2569
• DOI: 10.1016/j.jelechem.2018.02.049

Nickel nanoparticles incorporated with graphene oxide composite-glassy carbon electrode (Ni-GO/GCE) was constructed via a facile electrochemical method for sensitive and selective determination of rutin. The surface morphology, surface chemistry and conductance of the prepared electrodes were characterized by scanning electron microscopy (SEM), high resolution transmission electron microscopy (HRTEM), X-Ray photoelectron spectroscopy (XPS) and electrochemical impedance spectroscopy (EIS). The electrochemical behaviour of rutin on the Ni-GO/GCE was investigated by using of cyclic voltammetry technique. The composite electrode was also used for the detection of rutin with square wave voltammetry. The results indicated that under optimized conditions, the anodic peak current (Ipa) of rutin was found to be proportional to its concentration over two linear ranges 1.1 × 10−8–1.0 × 10−6 mol L−1 and 2.2 × 10−6–1.5 × 10−5 mol L−1, and a low detection limit of 3.2 × 10−9 mol L−1 was observed with the developed electrode. Interference studies were also performed in the presence of inorganic and organic compounds. Moreover, the Ni-GO/GCE was successfully applied for the determination of rutin in pharmaceutical formulations and remarkable sensitivity with acceptable recoveries were obtained. [Display omitted] •Ni-NiO particles was fabricated on GO/GCE using electrochemical methods.•The composite electrode was characterized with SEM, XPS, TEM and EIS techniques.•The Ni-GO/GCE showed excellent electrocatalytical properties to the rutin analysis.•The Ni-GO/GCE was used for the determination of rutin in pharmaceutical formulations.