Furofuran lignans from the Simpson Desert species Eremophila macdonnellii

The Eremophila plant family, which occurs in the arid zones of Australia, have witnessed extensive investigation, mostly inspired by Aboriginal traditional medicine. A wide and varied biological and phytochemical profile has been reported for over 18 individual species of Australian Eremophila, alth...

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Bibliographic Details
Published in:Fitoterapia 2018-04, Vol.126, p.93-97
Main Authors: Tan, Yuen P., Savchenko, Andrei I., Broit, Natasa, Boyle, Glen M., Parsons, Peter G., Williams, Craig M.
Format: Article
Language:English
Subjects:
Anticancer properties
Arid environments
Aridity
Australian Desert
Biological activity
Breast cancer
Cancer
Deserts
Eremophila
Flowers & plants
Lignan
Lignans
Natural product
Plant natural product
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Summary:The Eremophila plant family, which occurs in the arid zones of Australia, have witnessed extensive investigation, mostly inspired by Aboriginal traditional medicine. A wide and varied biological and phytochemical profile has been reported for over 18 individual species of Australian Eremophila, although E. macdonnellii from the Simpson Desert has not yet been investigated. Isolation and elucidation of one new and six known furofuran lignans are reported. The new lignan, epimethoxypiperitol, displayed moderate anti-cancer activity against the breast cancer cell line (MCF-7). [Display omitted]
ISSN:0367-326X
1873-6971
DOI:10.1016/j.fitote.2017.06.004