Rational tangle surgery and Xer recombination on catenanes

The protein recombinase can change the knot type of circular DNA. The action of a recombinase converting one knot into another knot is normally mathematically modeled by band surgery. Band surgeries on a 2-bridge knot N((4mn-1)/(2m)) yielding a (2,2k)-torus link are characterized. We apply this and...

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Bibliographic Details
Published in:arXiv.org 2011-08
Main Authors: Darcy, Isabel K, Ishihara, Kai, Medikonduri, Ram K, Shimokawa, Koya
Format: Article
Language:English
Subjects:
Deoxyribonucleic acid
DNA
Proteins
Surgery
Toruses
Online Access:Get full text
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Summary:The protein recombinase can change the knot type of circular DNA. The action of a recombinase converting one knot into another knot is normally mathematically modeled by band surgery. Band surgeries on a 2-bridge knot N((4mn-1)/(2m)) yielding a (2,2k)-torus link are characterized. We apply this and other rational tangle surgery results to analyze Xer recombination on DNA catenanes using the tangle model for protein-bound DNA.
ISSN:2331-8422
DOI:10.48550/arxiv.1108.0724