Loading…
Blood‐Catalyzed RAFT Polymerization
The use of hemoglobin (Hb) contained within red blood cells to drive a controlled radical polymerization via a reversible addition‐fragmentation chain transfer (RAFT) process is reported for the first time. No pre‐treatment of the Hb or cells was required prior to their use as polymerization catalys...
Saved in:
| Published in: | Angewandte Chemie 2018-08, Vol.130 (32), p.10445-10449 |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c2024-e62f4c1ac5b467b12509e98e5e8b6359525cc7920364bd5f2d046084cd920c683 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c2024-e62f4c1ac5b467b12509e98e5e8b6359525cc7920364bd5f2d046084cd920c683 |
| container_end_page | 10449 |
| container_issue | 32 |
| container_start_page | 10445 |
| container_title | Angewandte Chemie |
| container_volume | 130 |
| creator | Reyhani, Amin Nothling, Mitchell D. Ranji‐Burachaloo, Hadi McKenzie, Thomas G. Fu, Qiang Tan, Shereen Bryant, Gary Qiao, Greg G. |
| description | The use of hemoglobin (Hb) contained within red blood cells to drive a controlled radical polymerization via a reversible addition‐fragmentation chain transfer (RAFT) process is reported for the first time. No pre‐treatment of the Hb or cells was required prior to their use as polymerization catalysts, indicating the potential for synthetic engineering in complex biological microenvironments without the need for ex vivo techniques. Owing to the naturally occurring prevalence of the reagents employed in the catalytic system (Hb and hydrogen peroxide), this approach may facilitate the development of new strategies for in vivo cell engineering with synthetic macromolecules.
Hämoglobin (Hb) in roten Blutkörperchen wurde für eine kontrollierte radikalische Polymerisation über einen RAFT‐Prozess genutzt. Ohne Vorbehandlung konnten Hb oder Zellen als Polymerisationskatalysatoren verwendet werden, was auf die Möglichkeit synthetischer Modifizierungen in komplexen biologischen Mikroumgebungen ohne Einsatz von Ex‐vivo‐Techniken hindeutet. |
| doi_str_mv | 10.1002/ange.201802544 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2078575440</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2078575440</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2024-e62f4c1ac5b467b12509e98e5e8b6359525cc7920364bd5f2d046084cd920c683</originalsourceid><addsrcrecordid>eNqFkE1Lw0AQhhdRsFavngviMXV2sp_HWNoqFBWp52Wz2UhK2q2bFklP_gR_o7_ElIoePQ0Mz_MO8xJySWFIAfDGrl79EIEqQM7YEelRjjRJJZfHpAfAWKKQ6VNy1jQLABAodY9c39YhFF8fnyO7sXW788XgOZvMB0-hbpc-Vju7qcLqnJyUtm78xc_sk5fJeD66S2aP0_tRNkscArLECyyZo9bxnAmZU-SgvVaee5WLlGuO3DmpEVLB8oKXWAAToJgrup0TKu2Tq0PuOoa3rW82ZhG2cdWdNAhScdk9Bh01PFAuhqaJvjTrWC1tbA0Fs6_C7Kswv1V0gj4I71Xt239okz1Mx3_uN0rKYMQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2078575440</pqid></control><display><type>article</type><title>Blood‐Catalyzed RAFT Polymerization</title><source>Wiley-Blackwell Read & Publish Collection</source><creator>Reyhani, Amin ; Nothling, Mitchell D. ; Ranji‐Burachaloo, Hadi ; McKenzie, Thomas G. ; Fu, Qiang ; Tan, Shereen ; Bryant, Gary ; Qiao, Greg G.</creator><creatorcontrib>Reyhani, Amin ; Nothling, Mitchell D. ; Ranji‐Burachaloo, Hadi ; McKenzie, Thomas G. ; Fu, Qiang ; Tan, Shereen ; Bryant, Gary ; Qiao, Greg G.</creatorcontrib><description>The use of hemoglobin (Hb) contained within red blood cells to drive a controlled radical polymerization via a reversible addition‐fragmentation chain transfer (RAFT) process is reported for the first time. No pre‐treatment of the Hb or cells was required prior to their use as polymerization catalysts, indicating the potential for synthetic engineering in complex biological microenvironments without the need for ex vivo techniques. Owing to the naturally occurring prevalence of the reagents employed in the catalytic system (Hb and hydrogen peroxide), this approach may facilitate the development of new strategies for in vivo cell engineering with synthetic macromolecules.
Hämoglobin (Hb) in roten Blutkörperchen wurde für eine kontrollierte radikalische Polymerisation über einen RAFT‐Prozess genutzt. Ohne Vorbehandlung konnten Hb oder Zellen als Polymerisationskatalysatoren verwendet werden, was auf die Möglichkeit synthetischer Modifizierungen in komplexen biologischen Mikroumgebungen ohne Einsatz von Ex‐vivo‐Techniken hindeutet.</description><identifier>ISSN: 0044-8249</identifier><identifier>EISSN: 1521-3757</identifier><identifier>DOI: 10.1002/ange.201802544</identifier><language>eng</language><publisher>Weinheim: Wiley Subscription Services, Inc</publisher><subject>Addition polymerization ; Catalysis ; Catalysts ; Chain transfer ; Chemistry ; Engineering ; Erythrocytes ; Hemoglobin ; Hydrogen peroxide ; Hämoglobin ; Macromolecules ; Microenvironments ; Polymerisationen ; Polymerization ; RAFT ; Reagents ; Rote Blutkörperchen</subject><ispartof>Angewandte Chemie, 2018-08, Vol.130 (32), p.10445-10449</ispartof><rights>2018 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2024-e62f4c1ac5b467b12509e98e5e8b6359525cc7920364bd5f2d046084cd920c683</citedby><cites>FETCH-LOGICAL-c2024-e62f4c1ac5b467b12509e98e5e8b6359525cc7920364bd5f2d046084cd920c683</cites><orcidid>0000-0003-2771-9675</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Reyhani, Amin</creatorcontrib><creatorcontrib>Nothling, Mitchell D.</creatorcontrib><creatorcontrib>Ranji‐Burachaloo, Hadi</creatorcontrib><creatorcontrib>McKenzie, Thomas G.</creatorcontrib><creatorcontrib>Fu, Qiang</creatorcontrib><creatorcontrib>Tan, Shereen</creatorcontrib><creatorcontrib>Bryant, Gary</creatorcontrib><creatorcontrib>Qiao, Greg G.</creatorcontrib><title>Blood‐Catalyzed RAFT Polymerization</title><title>Angewandte Chemie</title><description>The use of hemoglobin (Hb) contained within red blood cells to drive a controlled radical polymerization via a reversible addition‐fragmentation chain transfer (RAFT) process is reported for the first time. No pre‐treatment of the Hb or cells was required prior to their use as polymerization catalysts, indicating the potential for synthetic engineering in complex biological microenvironments without the need for ex vivo techniques. Owing to the naturally occurring prevalence of the reagents employed in the catalytic system (Hb and hydrogen peroxide), this approach may facilitate the development of new strategies for in vivo cell engineering with synthetic macromolecules.
Hämoglobin (Hb) in roten Blutkörperchen wurde für eine kontrollierte radikalische Polymerisation über einen RAFT‐Prozess genutzt. Ohne Vorbehandlung konnten Hb oder Zellen als Polymerisationskatalysatoren verwendet werden, was auf die Möglichkeit synthetischer Modifizierungen in komplexen biologischen Mikroumgebungen ohne Einsatz von Ex‐vivo‐Techniken hindeutet.</description><subject>Addition polymerization</subject><subject>Catalysis</subject><subject>Catalysts</subject><subject>Chain transfer</subject><subject>Chemistry</subject><subject>Engineering</subject><subject>Erythrocytes</subject><subject>Hemoglobin</subject><subject>Hydrogen peroxide</subject><subject>Hämoglobin</subject><subject>Macromolecules</subject><subject>Microenvironments</subject><subject>Polymerisationen</subject><subject>Polymerization</subject><subject>RAFT</subject><subject>Reagents</subject><subject>Rote Blutkörperchen</subject><issn>0044-8249</issn><issn>1521-3757</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNqFkE1Lw0AQhhdRsFavngviMXV2sp_HWNoqFBWp52Wz2UhK2q2bFklP_gR_o7_ElIoePQ0Mz_MO8xJySWFIAfDGrl79EIEqQM7YEelRjjRJJZfHpAfAWKKQ6VNy1jQLABAodY9c39YhFF8fnyO7sXW788XgOZvMB0-hbpc-Vju7qcLqnJyUtm78xc_sk5fJeD66S2aP0_tRNkscArLECyyZo9bxnAmZU-SgvVaee5WLlGuO3DmpEVLB8oKXWAAToJgrup0TKu2Tq0PuOoa3rW82ZhG2cdWdNAhScdk9Bh01PFAuhqaJvjTrWC1tbA0Fs6_C7Kswv1V0gj4I71Xt239okz1Mx3_uN0rKYMQ</recordid><startdate>20180806</startdate><enddate>20180806</enddate><creator>Reyhani, Amin</creator><creator>Nothling, Mitchell D.</creator><creator>Ranji‐Burachaloo, Hadi</creator><creator>McKenzie, Thomas G.</creator><creator>Fu, Qiang</creator><creator>Tan, Shereen</creator><creator>Bryant, Gary</creator><creator>Qiao, Greg G.</creator><general>Wiley Subscription Services, Inc</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope><orcidid>https://orcid.org/0000-0003-2771-9675</orcidid></search><sort><creationdate>20180806</creationdate><title>Blood‐Catalyzed RAFT Polymerization</title><author>Reyhani, Amin ; Nothling, Mitchell D. ; Ranji‐Burachaloo, Hadi ; McKenzie, Thomas G. ; Fu, Qiang ; Tan, Shereen ; Bryant, Gary ; Qiao, Greg G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2024-e62f4c1ac5b467b12509e98e5e8b6359525cc7920364bd5f2d046084cd920c683</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Addition polymerization</topic><topic>Catalysis</topic><topic>Catalysts</topic><topic>Chain transfer</topic><topic>Chemistry</topic><topic>Engineering</topic><topic>Erythrocytes</topic><topic>Hemoglobin</topic><topic>Hydrogen peroxide</topic><topic>Hämoglobin</topic><topic>Macromolecules</topic><topic>Microenvironments</topic><topic>Polymerisationen</topic><topic>Polymerization</topic><topic>RAFT</topic><topic>Reagents</topic><topic>Rote Blutkörperchen</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Reyhani, Amin</creatorcontrib><creatorcontrib>Nothling, Mitchell D.</creatorcontrib><creatorcontrib>Ranji‐Burachaloo, Hadi</creatorcontrib><creatorcontrib>McKenzie, Thomas G.</creatorcontrib><creatorcontrib>Fu, Qiang</creatorcontrib><creatorcontrib>Tan, Shereen</creatorcontrib><creatorcontrib>Bryant, Gary</creatorcontrib><creatorcontrib>Qiao, Greg G.</creatorcontrib><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Angewandte Chemie</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Reyhani, Amin</au><au>Nothling, Mitchell D.</au><au>Ranji‐Burachaloo, Hadi</au><au>McKenzie, Thomas G.</au><au>Fu, Qiang</au><au>Tan, Shereen</au><au>Bryant, Gary</au><au>Qiao, Greg G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Blood‐Catalyzed RAFT Polymerization</atitle><jtitle>Angewandte Chemie</jtitle><date>2018-08-06</date><risdate>2018</risdate><volume>130</volume><issue>32</issue><spage>10445</spage><epage>10449</epage><pages>10445-10449</pages><issn>0044-8249</issn><eissn>1521-3757</eissn><abstract>The use of hemoglobin (Hb) contained within red blood cells to drive a controlled radical polymerization via a reversible addition‐fragmentation chain transfer (RAFT) process is reported for the first time. No pre‐treatment of the Hb or cells was required prior to their use as polymerization catalysts, indicating the potential for synthetic engineering in complex biological microenvironments without the need for ex vivo techniques. Owing to the naturally occurring prevalence of the reagents employed in the catalytic system (Hb and hydrogen peroxide), this approach may facilitate the development of new strategies for in vivo cell engineering with synthetic macromolecules.
Hämoglobin (Hb) in roten Blutkörperchen wurde für eine kontrollierte radikalische Polymerisation über einen RAFT‐Prozess genutzt. Ohne Vorbehandlung konnten Hb oder Zellen als Polymerisationskatalysatoren verwendet werden, was auf die Möglichkeit synthetischer Modifizierungen in komplexen biologischen Mikroumgebungen ohne Einsatz von Ex‐vivo‐Techniken hindeutet.</abstract><cop>Weinheim</cop><pub>Wiley Subscription Services, Inc</pub><doi>10.1002/ange.201802544</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0003-2771-9675</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0044-8249 |
| ispartof | Angewandte Chemie, 2018-08, Vol.130 (32), p.10445-10449 |
| issn | 0044-8249 1521-3757 |
| language | eng |
| recordid | cdi_proquest_journals_2078575440 |
| source | Wiley-Blackwell Read & Publish Collection |
| subjects | Addition polymerization Catalysis Catalysts Chain transfer Chemistry Engineering Erythrocytes Hemoglobin Hydrogen peroxide Hämoglobin Macromolecules Microenvironments Polymerisationen Polymerization RAFT Reagents Rote Blutkörperchen |
| title | Blood‐Catalyzed RAFT Polymerization |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-01T10%3A34%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Blood%E2%80%90Catalyzed%20RAFT%20Polymerization&rft.jtitle=Angewandte%20Chemie&rft.au=Reyhani,%20Amin&rft.date=2018-08-06&rft.volume=130&rft.issue=32&rft.spage=10445&rft.epage=10449&rft.pages=10445-10449&rft.issn=0044-8249&rft.eissn=1521-3757&rft_id=info:doi/10.1002/ange.201802544&rft_dat=%3Cproquest_cross%3E2078575440%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c2024-e62f4c1ac5b467b12509e98e5e8b6359525cc7920364bd5f2d046084cd920c683%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2078575440&rft_id=info:pmid/&rfr_iscdi=true |