Polyaniline-based glucose biosensor: A review

The aim of this review is to provide a detailed report of the glucose biosensor based on polyaniline. This conducting polymer not only has been widely used as matrix for immobilization of glucose oxidase, but also can act as electron mediator during enzymatic reaction process due to its outstanding...

Full description

Saved in:
Bibliographic Details
Published in:Journal of electroanalytical chemistry (Lausanne, Switzerland) Switzerland), 2016-12, Vol.782, p.138-153
Main Authors: Lai, Jiahui, Yi, Yingchun, Zhu, Ping, Shen, Jing, Wu, Kesen, Zhang, Lili, Liu, Jian
Format: Article
Language:English
Subjects:
Biocompatibility
Biosensor
Biosensors
Conducting polymers
Conjugation
Electrochemical analysis
Electrodes
Electron mediator
Enzyme electrodes
Enzymes
Glucose
Glucose oxidase
Nanomaterials
Nanostructure
Polyaniline
Polyanilines
Stability
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The aim of this review is to provide a detailed report of the glucose biosensor based on polyaniline. This conducting polymer not only has been widely used as matrix for immobilization of glucose oxidase, but also can act as electron mediator during enzymatic reaction process due to its outstanding features such as high conductivity, exceptional environmental stability in air, tunable electrochemical properties, biocompatibility, and more. In the paper, the early development history of conventional polyaniline for glucose biosensors is reviewed. And then the shift from conventional polyaniline matrix to composite matrices is discussed by focusing on improving the selectivity and stability of the glucose biosensor. Finally, because of their enhanced electrochemical reactivity, the nanostructured polyaniline and its conjugation with other nanomaterials are reviewed for developing high-performance glucose biosensors. Overall, the evolution of polyaniline is described in detail from conventional matrix to polyaniline composites and then to the nanostructured polyaniline for exploring a sensitive, stable and reliable glucose biosensor. •Conventional bulk polyaniline was a suitable matrix for GOx immobilization.•Polyaniline composites improved the selectivity and stability of glucose biosensors.•Polyaniline-based nanomaterials contributed to development of glucose biosensors with high performance.
ISSN:1572-6657
1873-2569
DOI:10.1016/j.jelechem.2016.10.033