Laparoscopic real-time en-face differential optical topography of near-surface heterogeneity by using an applicator probe with the maximum-density radially alternating illumination and detection fiber-channels

We demonstrate a laparoscopic applicator probe and a method thereof for real-time en-face topographic mapping of near-surface heterogeneity for potential use in intraoperative margin assessment during minimally invasive oncological procedures. The probe fits in a 12mm port and houses at its maximum...

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Bibliographic Details
Published in:arXiv.org 2016-08
Main Authors: Piao, Daqing, Bartels, Kenneth E, G Reed Holyoak, Patel, Sanjay
Format: Article
Language:English
Subjects:
Attenuation
Channels
Fibers
Field of view
Heterogeneity
Illumination
Laparoscopy
Light
Real time
Topographic mapping
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Summary:We demonstrate a laparoscopic applicator probe and a method thereof for real-time en-face topographic mapping of near-surface heterogeneity for potential use in intraoperative margin assessment during minimally invasive oncological procedures. The probe fits in a 12mm port and houses at its maximum 128 copper-coated 750um fibers that form radially alternating illumination (70 fibers) and detection (58 fibers) channels. By simultaneously illuminating the 70 source channels of the probe that is in contact with a scattering medium and concurrently measuring the light diffusely propagated to the 58 detector channels, the presence of near-surface optical heterogeneities can be resolved in an en-face 9.5mm field-of-view in real-time. Visualization of a subsurface margin of strong attenuation contrast at a depth up to 3mm is demonstrated at one wavelength at a frame rate of 1.25Hz.
ISSN:2331-8422