LC-MS/MS Identification of Novel Saponins from the Viscera of Sea Cucumber Apostichopus japonicus

Sea cucumbers, soft-bodied wormlike echinoderms, are traditionally consumed in China. Sea cucumber viscera are often discarded during production. In this study, we characterized saponins present in the viscera of the Chinese sea cucumber Apostichopus japonicus. Sea cucumber saponins were obtained by...

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Published in:Chemistry of natural compounds 2018-07, Vol.54 (4), p.721-725
Main Authors: Zhang, Xuan-Ming, Li, Xiao-Bin, Zhang, Shan-Shan, He, Qiu-Xia, Hou, Hai-Rong, Dang, Li, Guo, Jing-Lan, Chen, Yu-Feng, Yu, Tao, Peng, De-Jie, Han, Li-Wen, Liu, Ke-Chun
Format: Article
Language:English
Subjects:
Fractionation
Industrial applications
Invertebrates
Medicine
Negative ions
NMR
Nuclear magnetic resonance
Organic Chemistry
Pharmacy
Plant Sciences
Saponins
Viscera
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cited_by cdi_FETCH-LOGICAL-c389t-f0cdd12fc34d0c01bef3a384cd48e0e93857779c54f6e036b262ea7eec75f6f83
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container_title Chemistry of natural compounds
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creator Zhang, Xuan-Ming
Li, Xiao-Bin
Zhang, Shan-Shan
He, Qiu-Xia
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Guo, Jing-Lan
Chen, Yu-Feng
Yu, Tao
Peng, De-Jie
Han, Li-Wen
Liu, Ke-Chun
description Sea cucumbers, soft-bodied wormlike echinoderms, are traditionally consumed in China. Sea cucumber viscera are often discarded during production. In this study, we characterized saponins present in the viscera of the Chinese sea cucumber Apostichopus japonicus. Sea cucumber saponins were obtained by a two-stage process consisting of foam fractionation and macroporous resin separation. Furthermore, the saponins were characterized by HPLC-Q-TOF-MS. Three novel saponins, i.e., apostichoposide A–C, were detected and characterized based on their unique fragmentation patterns in the negative ion mode tandem MS spectra as well as isolation and NMR studies. The abundance of saponins in sea cucumber viscera holds promise for industrial applications.
doi_str_mv 10.1007/s10600-018-2454-4
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subjects Fractionation
Industrial applications
Invertebrates
Medicine
Negative ions
NMR
Nuclear magnetic resonance
Organic Chemistry
Pharmacy
Plant Sciences
Saponins
Viscera
title LC-MS/MS Identification of Novel Saponins from the Viscera of Sea Cucumber Apostichopus japonicus
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