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Frontispiece: Recent Advances in the Synthesis of β‐Functionalized Ketones by Radical‐Mediated 1,2‐Rearrangement of Allylic Alcohols

β‐Functionalized ketones are highly important compounds that serve as versatile synthetic intermediates and building blocks in organic synthesis. Recently, radical‐mediated 1,2‐rearrangement reactions of allylic alcohols have provided a highly powerful and attractive strategy to prepare various dive...

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Bibliographic Details
Published in:Chemistry : a European journal 2018-08, Vol.24 (43), p.n/a
Main Authors: Weng, Wei‐Zhi, Zhang, Bo
Format: Article
Language:English
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Summary:β‐Functionalized ketones are highly important compounds that serve as versatile synthetic intermediates and building blocks in organic synthesis. Recently, radical‐mediated 1,2‐rearrangement reactions of allylic alcohols have provided a highly powerful and attractive strategy to prepare various diversely β‐functionalized ketones. This strategy allows the preparation of β‐functionalized ketones in a straightforward modular way with high regioselectivity, and various functional groups can be readily installed into the β‐position of cyclic and acyclic ketones by using different radical precursors. For an overview see the Minireview by W.‐Z. Weng and B. Zhang on page 10934 ff.
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.201884363