Towards a Radio-guided Surgery with \(\beta^{-}\) Decays: Uptake of a somatostatin analogue (DOTATOC) in Meningioma and High Grade Glioma

A novel radio guided surgery (RGS) technique for cerebral tumors using \(\beta^{-}\) radiation is being developed. Checking the availability of a radio-tracer that can deliver a \(\beta^{-}\) emitter to the tumor is a fundamental step in the deployment of such technique. This paper reports a study o...

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Published in:arXiv.org 2014-12
Main Authors: Collamati, Francesco, Pepe, Alessandra, Bellini, Fabio, Bocci, Valerio, Cremonesi, Marta, De Lucia, Erika, Ferrari, Mahila, Frallicciardi, Paola M, Grana, Chiara M, Marafini, Michela, Mattei, Ilaria, Morganti, Silvio, Patera, Vincenzo, Piersanti, Luca, Recchia, Luigi, Russomando, Andrea, Sarti, Alessio, Sciubba, Adalberto, Senzacqua, Martina, Elena Solfaroli Camillocci, Voena, Cecilia, Faccini, Riccardo
Format: Article
Language:English
Subjects:
Beta decay
Beta rays
Emitters
Feasibility studies
Radio
Surgery
Tumors
Online Access:Get full text
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Summary:A novel radio guided surgery (RGS) technique for cerebral tumors using \(\beta^{-}\) radiation is being developed. Checking the availability of a radio-tracer that can deliver a \(\beta^{-}\) emitter to the tumor is a fundamental step in the deployment of such technique. This paper reports a study of the uptake of 90Y labeled (DOTATOC) in the meningioma and the high grade glioma (HGG) and a feasibility study of the RGS technique in these cases.
ISSN:2331-8422
DOI:10.48550/arxiv.1412.7389