The statistical properties of protein folding in the {\phi}^4 theory

The statistical properties of protein folding within the {\phi}^4 model are investigated. The calculation is performed using statistical mechanics and path integral method. In particular, the evolution of heat capacity in term of temperature is given for various levels of the nonlinearity of source...

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Bibliographic Details
Published in:arXiv.org 2012-01
Main Authors: Januar, M, Sulaiman, A, Handoko, L T
Format: Article
Language:English
Subjects:
Backbone
Computer simulation
Energy absorption
Folding
Nonlinearity
Protein folding
Proteins
Statistical mechanics
Online Access:Get full text
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Summary:The statistical properties of protein folding within the {\phi}^4 model are investigated. The calculation is performed using statistical mechanics and path integral method. In particular, the evolution of heat capacity in term of temperature is given for various levels of the nonlinearity of source and the strength of interaction between protein backbone and nonlinear source. It is found that the nonlinear source contributes constructively to the specific heat especially at higher temperature when it is weakly interacting with the protein backbone. This indicates increasing energy absorption as the intensity of nonlinear sources are getting greater. The simulation of protein folding dynamics within the model is also refined.
ISSN:2331-8422
DOI:10.48550/arxiv.1112.4712