Lateral resolution enhancement of pulse-driven light-addressable potentiometric sensor

•New LAPS-driving method utilizing a pulsed light beam.•Improvement of the lateral resolution by a factor of 2.8–6.2.•Improvement of the contrast of a line scan by a factor of 2.4–3.2. To study chemical and biological processes, spatially resolved determination of the concentrations of one or more a...

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Bibliographic Details
Published in:Sensors and actuators. B, Chemical Chemical, 2017-09, Vol.248, p.961-965
Main Authors: Werner, Carl Frederik, Miyamoto, Ko-ichiro, Wagner, Torsten, Schöning, Michael J., Yoshinobu, Tatsuo
Format: Article
Language:English
Subjects:
Aqueous solutions
Biological activity
Chemical images
Excitation
LAPS
Light-addressable potentiometric sensor
Organic chemistry
Scientific imaging
Semiconductors
Sensors
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Summary:•New LAPS-driving method utilizing a pulsed light beam.•Improvement of the lateral resolution by a factor of 2.8–6.2.•Improvement of the contrast of a line scan by a factor of 2.4–3.2. To study chemical and biological processes, spatially resolved determination of the concentrations of one or more analyte species is of distinct interest. With a light-addressable potentiometric sensor (LAPS), chemical images can be created, which visualize the concentration distribution above the sensor plate. One important challenge is to achieve a good lateral resolution in order to detect events that take place in a small and limited region. LAPS utilizes a focused light spot to address the measurement region. By moving this light spot along the semiconductor sensor plate, the concentration distribution can be observed. In this study, we show that utilizing a pulse as light excitation instead of a traditionally used continuously modulated light excitation, the lateral resolution can be improved by a factor of 6 or more.
ISSN:0925-4005
1873-3077
DOI:10.1016/j.snb.2017.02.057