Loading…
Biological potential of oxo-vanadium salicylediene amino-acid complexes as cytotoxic, antimicrobial, antioxidant and DNA interaction
New series of oxo-vanadium N-salicyledieneamino acid Schiff base complexes are synthesized and characterized. They are synthesized from the reaction of sodium salicylaldehyde-5-sulfonate, some amino acids, alanine (VOHL1), leucine (VOHL2) or glycine (VOHL3) in an aqueous media, and leucine (VOHLpy1)...
Saved in:
Published in: | Journal of photochemistry and photobiology. B, Biology Biology, 2018-07, Vol.184, p.34-43 |
---|---|
Main Authors: | , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | cdi_FETCH-LOGICAL-c402t-b7390e0d681cf542495d7da31919b97cbb86200d9a4afbcb2889c09e26fc3e33 |
---|---|
cites | cdi_FETCH-LOGICAL-c402t-b7390e0d681cf542495d7da31919b97cbb86200d9a4afbcb2889c09e26fc3e33 |
container_end_page | 43 |
container_issue | |
container_start_page | 34 |
container_title | Journal of photochemistry and photobiology. B, Biology |
container_volume | 184 |
creator | Adam, Mohamed Shaker S. Elsawy, Hany |
description | New series of oxo-vanadium N-salicyledieneamino acid Schiff base complexes are synthesized and characterized. They are synthesized from the reaction of sodium salicylaldehyde-5-sulfonate, some amino acids, alanine (VOHL1), leucine (VOHL2) or glycine (VOHL3) in an aqueous media, and leucine (VOHLpy1) or tryptophan (VOHLpy2) in pyridine with vanadyl acetylacetonate. The complexes are characterized by EA, TGA, IR, UV–Visible and mass spectra, conductivity and magnetic measurements. The biological activity of the VO-complexes shows that VOHL1, VOHL2 and VOHL3 exhibit anti-proliferative effect and may be used as anticancer drugs. VO-complexes manifest high toxicity, except VOHL2 is less toxic, and could be applied for the human being. VOHL1, VOHL2 and VOHL3 display remarkable SOD like potential and act as high inhibiting reagents. VOHLpy1 and VOHLpy2 show low inhibiting potentials. VO-complexes have good anti-oxidant effect, in which VOHL3 affords the best antioxidant activity. The interaction between VO-complexes and DNA is studied spectrophotometrically and by gel electrophoresis. Binding constants and spectrophotometric parameters indicate a strong interaction between VO-complexes and DNA. VO-complexes have respectable anti–bacterial and antifungal activities, where VOHL3 shows the maximum potential. DFT calculations of VOHL1 and VOHL3 were discussed in the light of their biological activity, which are convenient with the obtained results.
[Display omitted]
•New series of oxo-vanadium N-salicyledieneamino acid Schiff base complexes were synthesized and characterized.•They have high anti-proliferative effect and may be used as anticancer drugs.•They display a remarkable SOD like potential and act as high inhibiting reagents. They have also high potential as antioxidant, antibacterial and antifungal reagents.•Strong interaction between VO-complexes and DNA was detected spectrophotometrically and by gel electrophoresis.•Theoretical results (DFT calculations) are in good agreement with the experimental data. |
doi_str_mv | 10.1016/j.jphotobiol.2018.05.002 |
format | article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2088799366</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1011134418300046</els_id><sourcerecordid>2088799366</sourcerecordid><originalsourceid>FETCH-LOGICAL-c402t-b7390e0d681cf542495d7da31919b97cbb86200d9a4afbcb2889c09e26fc3e33</originalsourceid><addsrcrecordid>eNqFkM1u1TAQhS1ERUvhFZAltiSMnT972ZaWVqrKpnvLsSfgKImDnVvdu-fBmeoWWOLNzGjOnBl_jHEBpQDRfh7Lcf0Rt9iHOJUShCqhKQHkK3YmVFcVslXyNeUgRCGquj5lb3MegV7Tdm_YqdRdp5TqztivS7KI34OzE1_jhssWKIsDj_tYPNnF-rCbebZTcIcJfcAFuZ3DEgvrgucuzuuEe8zcZu4OG920D-4Tt-QzB5foQjsdS2p4ipR7_uXhgodlw2QdNZZ37GSwU8b3L_GcPd5cP17dFvffvt5dXdwXrga5FX1XaUDwrRJuaGpZ68Z33lZCC93rzvW9aiWA17a2Q-96qZR2oFG2g6uwqs7Zx6PtmuLPHebNjHGXFtpoJBANrau2JZU6quj6nBMOZk1htulgBJhn-mY0_-ibZ_oGGkP0afTDy4JdP6P_O_gHNwkujwKkXz4FTCY7QuoIbEK3GR_D_7f8BgpinmE</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2088799366</pqid></control><display><type>article</type><title>Biological potential of oxo-vanadium salicylediene amino-acid complexes as cytotoxic, antimicrobial, antioxidant and DNA interaction</title><source>Elsevier</source><creator>Adam, Mohamed Shaker S. ; Elsawy, Hany</creator><creatorcontrib>Adam, Mohamed Shaker S. ; Elsawy, Hany</creatorcontrib><description>New series of oxo-vanadium N-salicyledieneamino acid Schiff base complexes are synthesized and characterized. They are synthesized from the reaction of sodium salicylaldehyde-5-sulfonate, some amino acids, alanine (VOHL1), leucine (VOHL2) or glycine (VOHL3) in an aqueous media, and leucine (VOHLpy1) or tryptophan (VOHLpy2) in pyridine with vanadyl acetylacetonate. The complexes are characterized by EA, TGA, IR, UV–Visible and mass spectra, conductivity and magnetic measurements. The biological activity of the VO-complexes shows that VOHL1, VOHL2 and VOHL3 exhibit anti-proliferative effect and may be used as anticancer drugs. VO-complexes manifest high toxicity, except VOHL2 is less toxic, and could be applied for the human being. VOHL1, VOHL2 and VOHL3 display remarkable SOD like potential and act as high inhibiting reagents. VOHLpy1 and VOHLpy2 show low inhibiting potentials. VO-complexes have good anti-oxidant effect, in which VOHL3 affords the best antioxidant activity. The interaction between VO-complexes and DNA is studied spectrophotometrically and by gel electrophoresis. Binding constants and spectrophotometric parameters indicate a strong interaction between VO-complexes and DNA. VO-complexes have respectable anti–bacterial and antifungal activities, where VOHL3 shows the maximum potential. DFT calculations of VOHL1 and VOHL3 were discussed in the light of their biological activity, which are convenient with the obtained results.
[Display omitted]
•New series of oxo-vanadium N-salicyledieneamino acid Schiff base complexes were synthesized and characterized.•They have high anti-proliferative effect and may be used as anticancer drugs.•They display a remarkable SOD like potential and act as high inhibiting reagents. They have also high potential as antioxidant, antibacterial and antifungal reagents.•Strong interaction between VO-complexes and DNA was detected spectrophotometrically and by gel electrophoresis.•Theoretical results (DFT calculations) are in good agreement with the experimental data.</description><identifier>ISSN: 1011-1344</identifier><identifier>EISSN: 1873-2682</identifier><identifier>DOI: 10.1016/j.jphotobiol.2018.05.002</identifier><identifier>PMID: 29778887</identifier><language>eng</language><publisher>Switzerland: Elsevier B.V</publisher><subject>Alanine ; Amino acids ; Amino Acids - chemistry ; Amino Acids - pharmacology ; Amino Acids - toxicity ; Anti-Infective Agents - chemistry ; Anti-Infective Agents - pharmacology ; Anti-Infective Agents - toxicity ; Antibacterial ; Antifungal ; Antifungal activity ; Antineoplastic drugs ; Antioxidant ; Antioxidants ; Antioxidants - chemistry ; Antioxidants - pharmacology ; Antioxidants - toxicity ; Antitumor agents ; Bacteria - drug effects ; Biological activity ; Cell Proliferation - drug effects ; Chemical synthesis ; Coordination Complexes - chemistry ; Coordination Complexes - pharmacology ; Coordination Complexes - toxicity ; Cytotoxicity ; Deoxyribonucleic acid ; DFT calculations ; DNA ; DNA - chemistry ; Drug resistance ; Electrophoresis ; Fungi - drug effects ; Fungicides ; Gel electrophoresis ; Glycine ; Imines ; Interaction parameters ; Leucine ; Magnetic measurement ; Mass spectra ; Microbial Sensitivity Tests ; Oxo-vanadium ; Pyridines ; Quantum Theory ; Reagents ; Salicylic Acid - chemistry ; Salicylic Acid - pharmacology ; Salicylic Acid - toxicity ; Schiff base ; Schiff Bases - chemistry ; Sodium ; Spectrophotometry ; Strong interactions (field theory) ; Toxicity ; Tryptophan ; Vanadium ; Vanadium - chemistry ; Vanadium - pharmacology ; Vanadium - toxicity</subject><ispartof>Journal of photochemistry and photobiology. B, Biology, 2018-07, Vol.184, p.34-43</ispartof><rights>2018 Elsevier B.V.</rights><rights>Copyright © 2018 Elsevier B.V. All rights reserved.</rights><rights>Copyright Elsevier BV Jul 2018</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c402t-b7390e0d681cf542495d7da31919b97cbb86200d9a4afbcb2889c09e26fc3e33</citedby><cites>FETCH-LOGICAL-c402t-b7390e0d681cf542495d7da31919b97cbb86200d9a4afbcb2889c09e26fc3e33</cites><orcidid>0000-0001-8826-3558</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29778887$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Adam, Mohamed Shaker S.</creatorcontrib><creatorcontrib>Elsawy, Hany</creatorcontrib><title>Biological potential of oxo-vanadium salicylediene amino-acid complexes as cytotoxic, antimicrobial, antioxidant and DNA interaction</title><title>Journal of photochemistry and photobiology. B, Biology</title><addtitle>J Photochem Photobiol B</addtitle><description>New series of oxo-vanadium N-salicyledieneamino acid Schiff base complexes are synthesized and characterized. They are synthesized from the reaction of sodium salicylaldehyde-5-sulfonate, some amino acids, alanine (VOHL1), leucine (VOHL2) or glycine (VOHL3) in an aqueous media, and leucine (VOHLpy1) or tryptophan (VOHLpy2) in pyridine with vanadyl acetylacetonate. The complexes are characterized by EA, TGA, IR, UV–Visible and mass spectra, conductivity and magnetic measurements. The biological activity of the VO-complexes shows that VOHL1, VOHL2 and VOHL3 exhibit anti-proliferative effect and may be used as anticancer drugs. VO-complexes manifest high toxicity, except VOHL2 is less toxic, and could be applied for the human being. VOHL1, VOHL2 and VOHL3 display remarkable SOD like potential and act as high inhibiting reagents. VOHLpy1 and VOHLpy2 show low inhibiting potentials. VO-complexes have good anti-oxidant effect, in which VOHL3 affords the best antioxidant activity. The interaction between VO-complexes and DNA is studied spectrophotometrically and by gel electrophoresis. Binding constants and spectrophotometric parameters indicate a strong interaction between VO-complexes and DNA. VO-complexes have respectable anti–bacterial and antifungal activities, where VOHL3 shows the maximum potential. DFT calculations of VOHL1 and VOHL3 were discussed in the light of their biological activity, which are convenient with the obtained results.
[Display omitted]
•New series of oxo-vanadium N-salicyledieneamino acid Schiff base complexes were synthesized and characterized.•They have high anti-proliferative effect and may be used as anticancer drugs.•They display a remarkable SOD like potential and act as high inhibiting reagents. They have also high potential as antioxidant, antibacterial and antifungal reagents.•Strong interaction between VO-complexes and DNA was detected spectrophotometrically and by gel electrophoresis.•Theoretical results (DFT calculations) are in good agreement with the experimental data.</description><subject>Alanine</subject><subject>Amino acids</subject><subject>Amino Acids - chemistry</subject><subject>Amino Acids - pharmacology</subject><subject>Amino Acids - toxicity</subject><subject>Anti-Infective Agents - chemistry</subject><subject>Anti-Infective Agents - pharmacology</subject><subject>Anti-Infective Agents - toxicity</subject><subject>Antibacterial</subject><subject>Antifungal</subject><subject>Antifungal activity</subject><subject>Antineoplastic drugs</subject><subject>Antioxidant</subject><subject>Antioxidants</subject><subject>Antioxidants - chemistry</subject><subject>Antioxidants - pharmacology</subject><subject>Antioxidants - toxicity</subject><subject>Antitumor agents</subject><subject>Bacteria - drug effects</subject><subject>Biological activity</subject><subject>Cell Proliferation - drug effects</subject><subject>Chemical synthesis</subject><subject>Coordination Complexes - chemistry</subject><subject>Coordination Complexes - pharmacology</subject><subject>Coordination Complexes - toxicity</subject><subject>Cytotoxicity</subject><subject>Deoxyribonucleic acid</subject><subject>DFT calculations</subject><subject>DNA</subject><subject>DNA - chemistry</subject><subject>Drug resistance</subject><subject>Electrophoresis</subject><subject>Fungi - drug effects</subject><subject>Fungicides</subject><subject>Gel electrophoresis</subject><subject>Glycine</subject><subject>Imines</subject><subject>Interaction parameters</subject><subject>Leucine</subject><subject>Magnetic measurement</subject><subject>Mass spectra</subject><subject>Microbial Sensitivity Tests</subject><subject>Oxo-vanadium</subject><subject>Pyridines</subject><subject>Quantum Theory</subject><subject>Reagents</subject><subject>Salicylic Acid - chemistry</subject><subject>Salicylic Acid - pharmacology</subject><subject>Salicylic Acid - toxicity</subject><subject>Schiff base</subject><subject>Schiff Bases - chemistry</subject><subject>Sodium</subject><subject>Spectrophotometry</subject><subject>Strong interactions (field theory)</subject><subject>Toxicity</subject><subject>Tryptophan</subject><subject>Vanadium</subject><subject>Vanadium - chemistry</subject><subject>Vanadium - pharmacology</subject><subject>Vanadium - toxicity</subject><issn>1011-1344</issn><issn>1873-2682</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNqFkM1u1TAQhS1ERUvhFZAltiSMnT972ZaWVqrKpnvLsSfgKImDnVvdu-fBmeoWWOLNzGjOnBl_jHEBpQDRfh7Lcf0Rt9iHOJUShCqhKQHkK3YmVFcVslXyNeUgRCGquj5lb3MegV7Tdm_YqdRdp5TqztivS7KI34OzE1_jhssWKIsDj_tYPNnF-rCbebZTcIcJfcAFuZ3DEgvrgucuzuuEe8zcZu4OG920D-4Tt-QzB5foQjsdS2p4ipR7_uXhgodlw2QdNZZ37GSwU8b3L_GcPd5cP17dFvffvt5dXdwXrga5FX1XaUDwrRJuaGpZ68Z33lZCC93rzvW9aiWA17a2Q-96qZR2oFG2g6uwqs7Zx6PtmuLPHebNjHGXFtpoJBANrau2JZU6quj6nBMOZk1htulgBJhn-mY0_-ibZ_oGGkP0afTDy4JdP6P_O_gHNwkujwKkXz4FTCY7QuoIbEK3GR_D_7f8BgpinmE</recordid><startdate>201807</startdate><enddate>201807</enddate><creator>Adam, Mohamed Shaker S.</creator><creator>Elsawy, Hany</creator><general>Elsevier B.V</general><general>Elsevier BV</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TK</scope><scope>7U7</scope><scope>C1K</scope><orcidid>https://orcid.org/0000-0001-8826-3558</orcidid></search><sort><creationdate>201807</creationdate><title>Biological potential of oxo-vanadium salicylediene amino-acid complexes as cytotoxic, antimicrobial, antioxidant and DNA interaction</title><author>Adam, Mohamed Shaker S. ; Elsawy, Hany</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c402t-b7390e0d681cf542495d7da31919b97cbb86200d9a4afbcb2889c09e26fc3e33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Alanine</topic><topic>Amino acids</topic><topic>Amino Acids - chemistry</topic><topic>Amino Acids - pharmacology</topic><topic>Amino Acids - toxicity</topic><topic>Anti-Infective Agents - chemistry</topic><topic>Anti-Infective Agents - pharmacology</topic><topic>Anti-Infective Agents - toxicity</topic><topic>Antibacterial</topic><topic>Antifungal</topic><topic>Antifungal activity</topic><topic>Antineoplastic drugs</topic><topic>Antioxidant</topic><topic>Antioxidants</topic><topic>Antioxidants - chemistry</topic><topic>Antioxidants - pharmacology</topic><topic>Antioxidants - toxicity</topic><topic>Antitumor agents</topic><topic>Bacteria - drug effects</topic><topic>Biological activity</topic><topic>Cell Proliferation - drug effects</topic><topic>Chemical synthesis</topic><topic>Coordination Complexes - chemistry</topic><topic>Coordination Complexes - pharmacology</topic><topic>Coordination Complexes - toxicity</topic><topic>Cytotoxicity</topic><topic>Deoxyribonucleic acid</topic><topic>DFT calculations</topic><topic>DNA</topic><topic>DNA - chemistry</topic><topic>Drug resistance</topic><topic>Electrophoresis</topic><topic>Fungi - drug effects</topic><topic>Fungicides</topic><topic>Gel electrophoresis</topic><topic>Glycine</topic><topic>Imines</topic><topic>Interaction parameters</topic><topic>Leucine</topic><topic>Magnetic measurement</topic><topic>Mass spectra</topic><topic>Microbial Sensitivity Tests</topic><topic>Oxo-vanadium</topic><topic>Pyridines</topic><topic>Quantum Theory</topic><topic>Reagents</topic><topic>Salicylic Acid - chemistry</topic><topic>Salicylic Acid - pharmacology</topic><topic>Salicylic Acid - toxicity</topic><topic>Schiff base</topic><topic>Schiff Bases - chemistry</topic><topic>Sodium</topic><topic>Spectrophotometry</topic><topic>Strong interactions (field theory)</topic><topic>Toxicity</topic><topic>Tryptophan</topic><topic>Vanadium</topic><topic>Vanadium - chemistry</topic><topic>Vanadium - pharmacology</topic><topic>Vanadium - toxicity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Adam, Mohamed Shaker S.</creatorcontrib><creatorcontrib>Elsawy, Hany</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Journal of photochemistry and photobiology. B, Biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Adam, Mohamed Shaker S.</au><au>Elsawy, Hany</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Biological potential of oxo-vanadium salicylediene amino-acid complexes as cytotoxic, antimicrobial, antioxidant and DNA interaction</atitle><jtitle>Journal of photochemistry and photobiology. B, Biology</jtitle><addtitle>J Photochem Photobiol B</addtitle><date>2018-07</date><risdate>2018</risdate><volume>184</volume><spage>34</spage><epage>43</epage><pages>34-43</pages><issn>1011-1344</issn><eissn>1873-2682</eissn><abstract>New series of oxo-vanadium N-salicyledieneamino acid Schiff base complexes are synthesized and characterized. They are synthesized from the reaction of sodium salicylaldehyde-5-sulfonate, some amino acids, alanine (VOHL1), leucine (VOHL2) or glycine (VOHL3) in an aqueous media, and leucine (VOHLpy1) or tryptophan (VOHLpy2) in pyridine with vanadyl acetylacetonate. The complexes are characterized by EA, TGA, IR, UV–Visible and mass spectra, conductivity and magnetic measurements. The biological activity of the VO-complexes shows that VOHL1, VOHL2 and VOHL3 exhibit anti-proliferative effect and may be used as anticancer drugs. VO-complexes manifest high toxicity, except VOHL2 is less toxic, and could be applied for the human being. VOHL1, VOHL2 and VOHL3 display remarkable SOD like potential and act as high inhibiting reagents. VOHLpy1 and VOHLpy2 show low inhibiting potentials. VO-complexes have good anti-oxidant effect, in which VOHL3 affords the best antioxidant activity. The interaction between VO-complexes and DNA is studied spectrophotometrically and by gel electrophoresis. Binding constants and spectrophotometric parameters indicate a strong interaction between VO-complexes and DNA. VO-complexes have respectable anti–bacterial and antifungal activities, where VOHL3 shows the maximum potential. DFT calculations of VOHL1 and VOHL3 were discussed in the light of their biological activity, which are convenient with the obtained results.
[Display omitted]
•New series of oxo-vanadium N-salicyledieneamino acid Schiff base complexes were synthesized and characterized.•They have high anti-proliferative effect and may be used as anticancer drugs.•They display a remarkable SOD like potential and act as high inhibiting reagents. They have also high potential as antioxidant, antibacterial and antifungal reagents.•Strong interaction between VO-complexes and DNA was detected spectrophotometrically and by gel electrophoresis.•Theoretical results (DFT calculations) are in good agreement with the experimental data.</abstract><cop>Switzerland</cop><pub>Elsevier B.V</pub><pmid>29778887</pmid><doi>10.1016/j.jphotobiol.2018.05.002</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0001-8826-3558</orcidid></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1011-1344 |
ispartof | Journal of photochemistry and photobiology. B, Biology, 2018-07, Vol.184, p.34-43 |
issn | 1011-1344 1873-2682 |
language | eng |
recordid | cdi_proquest_journals_2088799366 |
source | Elsevier |
subjects | Alanine Amino acids Amino Acids - chemistry Amino Acids - pharmacology Amino Acids - toxicity Anti-Infective Agents - chemistry Anti-Infective Agents - pharmacology Anti-Infective Agents - toxicity Antibacterial Antifungal Antifungal activity Antineoplastic drugs Antioxidant Antioxidants Antioxidants - chemistry Antioxidants - pharmacology Antioxidants - toxicity Antitumor agents Bacteria - drug effects Biological activity Cell Proliferation - drug effects Chemical synthesis Coordination Complexes - chemistry Coordination Complexes - pharmacology Coordination Complexes - toxicity Cytotoxicity Deoxyribonucleic acid DFT calculations DNA DNA - chemistry Drug resistance Electrophoresis Fungi - drug effects Fungicides Gel electrophoresis Glycine Imines Interaction parameters Leucine Magnetic measurement Mass spectra Microbial Sensitivity Tests Oxo-vanadium Pyridines Quantum Theory Reagents Salicylic Acid - chemistry Salicylic Acid - pharmacology Salicylic Acid - toxicity Schiff base Schiff Bases - chemistry Sodium Spectrophotometry Strong interactions (field theory) Toxicity Tryptophan Vanadium Vanadium - chemistry Vanadium - pharmacology Vanadium - toxicity |
title | Biological potential of oxo-vanadium salicylediene amino-acid complexes as cytotoxic, antimicrobial, antioxidant and DNA interaction |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T19%3A37%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Biological%20potential%20of%20oxo-vanadium%20salicylediene%20amino-acid%20complexes%20as%20cytotoxic,%20antimicrobial,%20antioxidant%20and%20DNA%20interaction&rft.jtitle=Journal%20of%20photochemistry%20and%20photobiology.%20B,%20Biology&rft.au=Adam,%20Mohamed%20Shaker%20S.&rft.date=2018-07&rft.volume=184&rft.spage=34&rft.epage=43&rft.pages=34-43&rft.issn=1011-1344&rft.eissn=1873-2682&rft_id=info:doi/10.1016/j.jphotobiol.2018.05.002&rft_dat=%3Cproquest_cross%3E2088799366%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c402t-b7390e0d681cf542495d7da31919b97cbb86200d9a4afbcb2889c09e26fc3e33%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2088799366&rft_id=info:pmid/29778887&rfr_iscdi=true |