Microfluidic Device for Continuous Magnetophoretic Separation of Red Blood Cells

This paper presents a microfluidic device for magnetophoretic separation red blood cells from blood under contionous flow. The separation method consist of continous flow of a blood sample (diluted in PBS) through a microfluidic channel which presents on the bottom "dots" of feromagnetic l...

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Bibliographic Details
Published in:arXiv.org 2008-05
Main Authors: Iliescu, Ciprian, Barbarini, Elena, Marioara Avram, G Xu, Avram, Andrei
Format: Article
Language:English
Subjects:
Blood
Erythrocytes
Magnetic fields
Microfluidic devices
Separation
Online Access:Get full text
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Summary:This paper presents a microfluidic device for magnetophoretic separation red blood cells from blood under contionous flow. The separation method consist of continous flow of a blood sample (diluted in PBS) through a microfluidic channel which presents on the bottom "dots" of feromagnetic layer. By appling a magnetic field perpendicular on the flowing direction, the feromagnetic "dots" generates a gradient of magnetic field which amplifies the magnetic force. As a result, the red blood cells are captured on the bottom of the microfluidic channel while the rest of the blood is collected at the outlet. Experimental results show that an average of 95 % of red blood cells are trapped in the device
ISSN:2331-8422