Synthesis of cobalt-based magnetic nanoporous carbon core-shell molecularly imprinted polymers for the solid-phase extraction of phthalate plasticizers in edible oil

• Published in: Analytical and bioanalytical chemistry 2018-10, Vol.410 (26), p.6943-6954
• Main Authors: Wu, Chaojun, He, Juan, Chen, Ningning, Li, Yuanyuan, Yuan, Linlin, Zhao, Dongxin, He, Lijun, Gu, Keren, Zhang, Shusheng
• Format: Article
• Language: English
• Subjects: Analytical Chemistry; Biochemistry; Carbon; Carbonization; Characterization and Evaluation of Materials; Chemical industry; Chemical synthesis; Chemistry; Chemistry and Materials Science; Cobalt; Commercialization; Edible fats and oils; Edible oils; Extraction (Chemistry); Food Science; Gas chromatography; Imprinted polymers; Iron oxides; Laboratory Medicine; Magnetic fields; Metal-organic frameworks; Methods; Monitoring/Environmental Analysis; Phthalate plasticizers; Phthalates; Plasticizers; Polymers; Research Paper; Solid phases
• ISSN: 1618-2642; 1618-2650
• DOI: 10.1007/s00216-018-1299-9

In this work, cobalt magnetic nanoporous carbon (Co-MNPC) is employed as an alternative to intensively used Fe 3 O 4 cores for the preparation of magnetic molecularly imprinted polymers (Co-MNPC@MIPs) for the first time. Co-MNPC was prepared by one-step carbonization of Zeolitic Imidazolate Framework-67 (ZIF-67). Compared with the traditional Fe 3 O 4 core, Co-MNPC showed a high specific surface area and large pore volumes. The prepared adsorbents, which could be rapidly collected from a matrix by external magnetic field, were applied for solid-phase extraction of phthalate plasticizers in edible oil. Several requisite extraction parameters were optimized to achieve desired extraction performance. Under the optimum extraction conditions, Co-MNPC@MIPs displayed better performance than commercialized columns. An analysis method based on Co-MNPC@MIPs coupled with gas chromatography (GC) was established. The linear range was 1–150 μg mL −1 , and the detection limit range was 0.010–0.025 μg mL −1 . The spiked recovery rate of the five phthalate plasticizers was 81.6–102.2%, with a relative standard deviation of 3.25–12.02%. Finally, the proposed method showed good feasibility for phthalate plasticizer extraction from edible oil.