Synthesis of ivermectin-4″,5-diyl[bis(N-methylcarbamate)]

New ivermectin-4″,5-diyl[bis( N -methylcarbamate)] was synthesized by the MoO 2 Cl 2 (DMF) 2 -catalyzed reaction of ivermectin with methyl isocyanate. The synthesized compound could find application as antiparasitic agent.

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Bibliographic Details
Published in:Russian chemical bulletin 2018-05, Vol.67 (5), p.833-835
Main Authors: Blinnikov, A. N., Chernoburova, E. I., Kolotyrkina, N. G., Shchetinina, M. A., Lishchuk, V. A., Ovchinnikov, K. L., Kolobov, A. V., Dzhafarov, M. Kh, Vasilevich, F. I., Zavarzin, I. V.
Format: Article
Language:English
Subjects:
Chemical synthesis
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Full Articles
Industrial accidents
Inorganic Chemistry
Isocyanates
Methyl isocyanate
Organic Chemistry
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Description
Summary:New ivermectin-4″,5-diyl[bis( N -methylcarbamate)] was synthesized by the MoO 2 Cl 2 (DMF) 2 -catalyzed reaction of ivermectin with methyl isocyanate. The synthesized compound could find application as antiparasitic agent.
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-018-2145-0