Sustainable strategies for large-scale nanotechnology manufacturing in the biomedical field

Nanoscience is a powerful tool to study matter at the scale where cooperative actions among atomic and molecular assemblies are effective, that is, in the nanometer range. Its application to technology is expected to bring new ways to improve our life by means of applications in fields such as envir...

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Bibliographic Details
Published in:Green chemistry : an international journal and green chemistry resource : GC 2018, Vol.2 (17), p.3897-397
Main Authors: Falsini, S, Bardi, U, Abou-Hassan, A, Ristori, S
Format: Article
Language:English
Subjects:
Biomedical materials
Continuous flow
Environmental impact
Formulations
Green chemistry
Life cycle analysis
Life cycle assessment
Life cycle engineering
Life cycles
Materials science
Materials selection
Nanotechnology
Organic chemistry
Sustainability
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Summary:Nanoscience is a powerful tool to study matter at the scale where cooperative actions among atomic and molecular assemblies are effective, that is, in the nanometer range. Its application to technology is expected to bring new ways to improve our life by means of applications in fields such as environmental and materials science, pharmacy, and medicine. Given the progress in these areas, it is not too early to think in terms of large-scale production for nanotechnology-based products. At the same time, the consequence of a large-scale expansion of nanomanufacturing processes has not received sufficient attention so far, especially in terms of environmental impact. In this review, we highlight the issue of nanotechnology sustainability for biomedical applications. In particular, we discuss how (i) Life Cycle Assessment (LCA) models may help in guiding the choice of production processes; (ii) green chemistry can provide safe and environment friendly synthetic routes; and (iii) continuous flow methods may be implemented at large scale to give reproducible and highly controlled formulations for nanomedicine. Sustainable strategies for nanomedicine manufacture from the cradle to the grave.
ISSN:1463-9262
1463-9270
DOI:10.1039/c8gc01248b