Effect of Morus alba against Hyperglycemic and Hyperlipidemic Activities in Streptozotocin Induced Diabetic Nephropathy

The present study was designed to investigate the antihyperglycemic and hypolipidemic activities of ethanolic leaf extract of Morus alba (EMA) in Streptozotocin induced diabetic rats. Blood glucose, serum parameters such as glycated haemoglobin (HbA1c), bilirubin, albumin, creatinine, total protein,...

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Bibliographic Details
Published in:Biosciences, biotechnology research Asia biotechnology research Asia, 2017-12, Vol.14 (4), p.1441-1447
Main Authors: Swathi, P., Gana Manjusha, K., Vivekanand, M., Ramkishan, A., Bhavani, B.
Format: Article
Language:English
Subjects:
Animals
Antioxidants
Bilirubin
Cholesterol
Creatinine
Diabetes
Diabetes mellitus
Enzymes
Free radicals
Glucose
Hemoglobin
Herbal medicine
Hyperglycemia
Kidneys
Lipids
Metabolism
Metabolites
Morus alba
Nephropathy
Oxidative stress
Parameters
Proteins
Rats
Reduction
Rodents
Sterols
Streptozocin
Terpenes
Urea
Urine
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Summary:The present study was designed to investigate the antihyperglycemic and hypolipidemic activities of ethanolic leaf extract of Morus alba (EMA) in Streptozotocin induced diabetic rats. Blood glucose, serum parameters such as glycated haemoglobin (HbA1c), bilirubin, albumin, creatinine, total protein, urea, lipid profile, and urine parameters such as urine protein, creatinine and volume and renal antioxidant enzymes like SOD, CAT, GSH and MDA were estimated at the end of 12 weeks study period. Kidney histopathology was also done. The treatment with EMA showed significant (p
ISSN:0973-1245
2456-2602
DOI:10.13005/bbra/2589