Medical Materials Based on Chitosan Succinamide–Glycerol Systems

The conditions to obtain materials with elastic-viscous properties based on chitosan succinamide have been studied. A decreased polymer content and a transition from visco-elastic liquids to elastic-viscous systems were shown upon the addition of glycerol to an aqueous solution of chitosan succinami...

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Bibliographic Details
Published in:Applied biochemistry and microbiology 2018-09, Vol.54 (5), p.474-477
Main Authors: Bazunova, M. V., Sharafutdinova, L. A., Lazdin, R. Yu, Chernova, V. V., Mixonov, D. N., Zakharov, V. P.
Format: Article
Language:English
Subjects:
Biochemistry
Biomedical and Life Sciences
Chitosan
Glycerol
Laboratory animals
Life Sciences
Medical Microbiology
Microbiology
Polymers
Succinamide
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Summary:The conditions to obtain materials with elastic-viscous properties based on chitosan succinamide have been studied. A decreased polymer content and a transition from visco-elastic liquids to elastic-viscous systems were shown upon the addition of glycerol to an aqueous solution of chitosan succinamide. The systemic response, biological compatibility, and dynamics of bioresorbability of the obtained materials were studied during implantation in laboratory animals.
ISSN:0003-6838
1608-3024
DOI:10.1134/S0003683818050058