TNF-α inhibits SP-A gene expression in lung epithelial cells via p38 MAPK

Researchers have concluded that tumor necrosis factor-alpha downregulates surfactant protein A gene expression in lung epithelial cells via the p38 mitogen-activated protein kinase signal transduction pathway.

Saved in:
Bibliographic Details
Published in:American journal of physiology. Lung cellular and molecular physiology 2002-08, Vol.27 (2), p.L418-L427
Main Authors: MIAKOTINA, Olga L, SNYDER, Jeanne M
Format: Article
Language:English
Subjects:
Air breathing
Biological and medical sciences
Cells
Enzymes
Fundamental and applied biological sciences. Psychology
Lungs
Proteins
Respiratory system: anatomy, metabolism, gas exchange, ventilatory mechanics, respiratory hemodynamics
Tumors
Vertebrates: respiratory system
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Researchers have concluded that tumor necrosis factor-alpha downregulates surfactant protein A gene expression in lung epithelial cells via the p38 mitogen-activated protein kinase signal transduction pathway.
ISSN:1040-0605
1522-1504