An electrogenic amino acid transporter in the apical membrane of cultured human bronchial epithelial cells

We performed Ussing chamber experiments on cultured human bronchial epithelial cells to look for the presence of electrogenic dibasic amino acid transport. Apical but not basolateral L-arginine (10-1,000 micro M) increased the short-circuit current.

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Bibliographic Details
Published in:American journal of physiology. Lung cellular and molecular physiology 1998-11, Vol.19 (5), p.L917-L923
Main Authors: GALIETTA, L. J. V, MUSANTE, L, ZEGARRA-MORAN, O, ROMIO, L, CARUSO, U, FANTASIA, A, GAZZOLO, A, ROMANO, L, SACCO, O, ROSSI, G. A, VARESIO, L
Format: Article
Language:English
Subjects:
Amino acids
Biological and medical sciences
Cells
Gastroenterology. Liver. Pancreas. Abdomen
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Lungs
Medical sciences
Membranes
Other diseases. Semiology
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Description
Summary:We performed Ussing chamber experiments on cultured human bronchial epithelial cells to look for the presence of electrogenic dibasic amino acid transport. Apical but not basolateral L-arginine (10-1,000 micro M) increased the short-circuit current.
ISSN:1040-0605
1522-1504