Overexpression of tumor necrosis factor-α produces an increase in lung volumes and pulmonary hypertension

Fujita, Masaki, John M. Shannon, Charles G. Irvin, Karen A. Fagan, Carlyne Cool, Andrei Augustin, and Robert J. Mason. Overexpression of tumor necrosis factor-alpha produces an increase in lung volumes and pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 280: L39-L49, 2001.-Tumor necrosis...

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Published in:American journal of physiology. Lung cellular and molecular physiology 2001, Vol.24 (1), p.L39-L49
Main Authors: FUJITA, Masaki, SHANNON, John M, IRVIN, Charles G, FAGAN, Karen A, COOL, Carlyne, AUGUSTIN, Andrei, MASON, Robert J
Format: Article
Language:English
Subjects:
Anatomy & physiology
Biological and medical sciences
Emphysema
Hypertension
Lungs
Medical sciences
Pneumology
Respiratory system : syndromes and miscellaneous diseases
Tumors
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Summary:Fujita, Masaki, John M. Shannon, Charles G. Irvin, Karen A. Fagan, Carlyne Cool, Andrei Augustin, and Robert J. Mason. Overexpression of tumor necrosis factor-alpha produces an increase in lung volumes and pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 280: L39-L49, 2001.-Tumor necrosis factor (TNF)-alpha is a key proinflammatory cytokine that is thought to be important in the development of pulmonary fibrosis, whereas its role in pulmonary emphysema has not been as thoroughly documented.
ISSN:1040-0605
1522-1504