Signal transduction and regulation of lung endothelial cell permeability. Interaction between calcium and cAMP

Pulmonary endothelium forms a semiselective barrier that regulates fluid balance and leukocyte trafficking. During the course of lung inflammation, neurohumoral mediators and oxidants act on endothelial cells to induce intercellular gaps permissive for transudation of proteinaceous fluid from blood...

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Bibliographic Details
Published in:American journal of physiology. Lung cellular and molecular physiology 1998-08, Vol.19 (2), p.L203-L222
Main Authors: MOORE, T. M, CHETHAM, P. M, KELLY, J. J, STEVENS, T
Format: Article
Language:English
Subjects:
Biological and medical sciences
Calcium
Cell physiology
Cells
Cellular biology
Fundamental and applied biological sciences. Psychology
Lungs
Membranes
Molecular and cellular biology
Permeability
Signal transduction
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Summary:Pulmonary endothelium forms a semiselective barrier that regulates fluid balance and leukocyte trafficking. During the course of lung inflammation, neurohumoral mediators and oxidants act on endothelial cells to induce intercellular gaps permissive for transudation of proteinaceous fluid from blood into the interstitium.
ISSN:1040-0605
1522-1504