Transglutaminase-mediated fibronectin multimerization in lung endothelial matrix in response to TNF-α

It is shown that increased cell surface transglutaminase after tumor necrosis factor-alpha exposure initiates the enhanced formation of nonreducible high molecular mass fibronectin multimers but did not cause either the disruption of the fibronectin matrix or the increase in endothelial monolayer pe...

Full description

Saved in:
Bibliographic Details
Published in:American journal of physiology. Lung cellular and molecular physiology 2000-07, Vol.23 (1), p.L161-L174
Main Authors: RUIHUA CHEN, BAOCHONG GAO, CANCAN HUANG, OLSEN, B, ROTUNDO, R. F, BLUMENSTOCK, F, SABA, T. M
Format: Article
Language:English
Subjects:
Biological and medical sciences
Blood vessels and receptors
Cells
Cellular biology
Fundamental and applied biological sciences. Psychology
Lungs
Vertebrates: cardiovascular system
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:It is shown that increased cell surface transglutaminase after tumor necrosis factor-alpha exposure initiates the enhanced formation of nonreducible high molecular mass fibronectin multimers but did not cause either the disruption of the fibronectin matrix or the increase in endothelial monolayer permeability.
ISSN:1040-0605
1522-1504