Transgenic overexpression of beta2-adrenergic receptors in airway epithelial cells decreases bronchoconstriction

Research results show that epithelial cell beta2-adrenergic receptors regulate airway responsiveness in vivo and that the bronchodilating effect of beta-agonists results from activation of receptors on both epithelial and smooth muscle cells.

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Bibliographic Details
Published in:American journal of physiology. Lung cellular and molecular physiology 2000-08, Vol.23 (2), p.L379
Main Authors: McGraw, Dennis W, bes, Susan L, Mak, Judith C W, Witte, David P
Format: Article
Language:English
Subjects:
Asthma
Cells
Muscular system
Proteins
Respiratory system
Online Access:Get full text
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Description
Summary:Research results show that epithelial cell beta2-adrenergic receptors regulate airway responsiveness in vivo and that the bronchodilating effect of beta-agonists results from activation of receptors on both epithelial and smooth muscle cells.
ISSN:1040-0605
1522-1504