Phagocytosis of particulate air pollutants by human alveolar macrophages stimulates the bone marrow

Mukae et al determined whether human alveolar macrophages (AMs) that phagocytose atmospheric particulate matter produce mediators capable of stimulating the bone marrow. It is concluded that mediators released from AMs after phagocytosis of particulate matter induce a systemic inflammatory response...

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Bibliographic Details
Published in:American journal of physiology. Lung cellular and molecular physiology 2000-11, Vol.23 (5), p.L924-L931
Main Authors: MUKAE, Hiroshi, HOGG, James C, ENGLISH, Dean, VINCENT, Renaud, VAN EEDEN, Stephan F
Format: Article
Language:English
Subjects:
Air
Air pollution
Biological and medical sciences
Bone marrow
Cells
Cytokines
Environmental pollutants toxicology
Leukocytes
Medical sciences
Toxicology
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Summary:Mukae et al determined whether human alveolar macrophages (AMs) that phagocytose atmospheric particulate matter produce mediators capable of stimulating the bone marrow. It is concluded that mediators released from AMs after phagocytosis of particulate matter induce a systemic inflammatory response that includes stimulation of the bone marrow.
ISSN:1040-0605
1522-1504