Electrical Activity of the Cerebral Structures and Regulatory Effects of NO, Steroid Hormones, and BDNF in Rats with Experimental Alcohol Addiction

In a chronic experiment on rats with induced alcohol addiction, it was shown that chronic alcoholization leads to decreases in the levels of cortisol and testosterone in the hypothalamus, amygdalar complex, and blood serum. Functional changes in the hippocampus and nucl. accumbens are believed to pl...

Full description

Saved in:
Bibliographic Details
Published in:Neurophysiology (New York) 2017-06, Vol.49 (3), p.234-236
Main Authors: Berchenko, O. G., Titkova, A. M., Veselovs’ka, O. V., Shlyakhova, A. V., Levicheva, N. O., Prikhod’ko, O. O.
Format: Article
Language:English
Subjects:
2017
Addictions
Alcoholism
Animal experimentation
Biological products
Biomedical and Life Sciences
Biomedicine
Brain-derived neurotrophic factor
Cortisol
Drug addiction
Glucocorticoids
Hypothalamus
June 7-11
Metabolites
Neurophysiology
Neurosciences
Nitric oxide
PROCEEDINGS OF THE VII CONGRESS OF THE UKRAINIAN NEUROSCIENCE SOCIETY (Kyiv
Steroid hormones
Testosterone
Withdrawal
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In a chronic experiment on rats with induced alcohol addiction, it was shown that chronic alcoholization leads to decreases in the levels of cortisol and testosterone in the hypothalamus, amygdalar complex, and blood serum. Functional changes in the hippocampus and nucl. accumbens are believed to play a leading role in the formation of the alcohol withdrawal syndrome. Under these conditions, the level of NO metabolites in the above structures decreases against the background of increased BDNF concentrations in blood serum.
ISSN:0090-2977
1573-9007
DOI:10.1007/s11062-017-9668-0