Effects of pea with barley and less-processed maize on glycaemic control in diabetic dogs

• Published in: British journal of nutrition 2018-10, Vol.120 (7), p.777-786
• Main Authors: Teixeira, Fabio A., Machado, Daniela P., Jeremias, Juliana T., Queiroz, Mariana R., Pontieri, Cristiana F. F., Brunetto, Marcio A.
• Format: Article
• Language: English
• Subjects: Animal sciences; Animals; Area Under Curve; Barley; Blood; Blood glucose; Blood Glucose - metabolism; Corn; Crossovers; Diabetes; Diabetes mellitus; Diabetes Mellitus - blood; Diet; Dietary Carbohydrates - blood; Dietary Carbohydrates - pharmacology; Dietary Fiber - administration & dosage; Dietary Proteins - administration & dosage; Dogs; Double-Blind Method; Extrusion; Fasting; Female; Food products; Fructosamine - blood; Glucose; Glucose monitoring; Hordeum - chemistry; Hyperglycemia; Hyperglycemia - blood; Hyperglycemia - etiology; Hyperglycemia - prevention & control; Hypoglycemia - blood; Hypoglycemia - etiology; Hypoglycemia - prevention & control; Hypoglycemic Agents - pharmacology; Insulin; Male; Monitoring systems; Nutrients; Nutrition research; Nutritional Endocrinology; Peas; Pisum sativum - chemistry; Protamine; Proteins; Random Allocation; Rank tests; Starch; Starch - blood; Starch - pharmacology; Veterinary colleges; Veterinary medicine; Zea mays - chemistry; Zoology
• ISSN: 0007-1145; 1475-2662
• DOI: 10.1017/S000711451800171X

The source of starch may interfere with glycaemic control in dogs, but few studies have evaluated these aspects in diabetic dogs. This study compared the effects of two isonutrient diets with different starch sources, peas and barley (PB) v. maize (Mi), on diabetic dogs. The Mi diet was processed in order to generate a lower starch gelatinisation index. In all, fifteen adult diabetic dogs without other conditions were included. The animals were fed two dry extruded rations with moderate levels of fat and starch and high levels of protein and fibre using a random, double-blind cross-over design. Glycaemic curves over 48 h were developed via continuous glucose monitoring after 60 d on each diet and with the same neutral protamine Hagedorn (NPH) insulin dosage. The following were compared: fasting, mean, maximum and minimum blood glucose, maximum and minimum glycaemia difference, glycaemic increment, area under the glycaemic curve, area under the glycaemic increment curve and serum fructosamine concentration. Paired t tests or Wilcoxon signed-rank tests were used to compare the amount of food and nutrients ingested and the dietary effects on glycaemic variables between the diets. Dogs fed the PB diet presented a lower average mean interstitial glucose (P=0·01), longer mean hypoglycaemic time (P