The science behind sorbent selection

By determining the water content and water activity of a product and generating temperature-dependent Sorption isotherms for all components in a package system, it is possible to model the internal conditions of the package system with time given constant external temperature and RH conditions. The...

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Bibliographic Details
Published in:Pharmaceutical technology Europe 2008-06, Vol.20 (6), p.27
Main Authors: Hurley, Thomas J, Solovyov, Stanislav E
Format: Article
Language:English
Subjects:
Adsorption
Equilibrium
Humidity
Packaging
Peer review
Pharmaceutical industry
Pharmaceuticals
Product lifecycle management
Selection
Sorbents
Studies
Online Access:Get full text
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Summary:By determining the water content and water activity of a product and generating temperature-dependent Sorption isotherms for all components in a package system, it is possible to model the internal conditions of the package system with time given constant external temperature and RH conditions. The entire package, including drug product and desiccant, acts as a complete system and will reach equilibrium with time.
ISSN:1753-7967